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Search term: YMR284W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YKU70
SGD link S000004897
Alternative ID YMR284W
Description Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
Synonyms YMR284W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2327 ACDHYP-

KOGs classification KOGs description
L
INFORMATION STORAGE AND PROCESSING
Replication, recombination and repair
DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g16970 GI:15219967
Caenorhabditis elegans (Cel) CE28984
(WBGene00000519)
GI:17555930 Q9U2D2
Drosophila melanogaster (Dme) 7299442
(FBgn0011774)
GI:17985997 Q23976
Homo sapiens (Hsa) Hs17437153_2 GI:17437153
Homo sapiens (Hsa) Hs22050378 GI:22050378
Homo sapiens (Hsa) Hs22056613 GI:22056613
Homo sapiens (Hsa) Hs4503841
(XRCC6)
GI:4503841 P12956
Saccharomyces cerevisiae (Sce) YMR284w
(S000004897)
GI:6323940 P32807
Schizosaccharomyces pombe (Spo) SPCC126.02c GI:19075945 O94395


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPCC126.02c
GO:0000790 nuclear chromatin C
TAS
SceS000004897
GO:0005575 cellular_component C
ND
HsaP12956
GO:0005624 membrane fraction C
TAS
HsaP12956
GO:0005634 nucleus C
IDA
SpoSPCC126.02c
NAS
DmeFBgn0011774
TAS
HsaP12956
GO:0005635 nuclear envelope C
IDA
SceS000004897
GO:0005667 transcription factor complex C
IDA
HsaP12956
GO:0005724 nuclear telomeric heterochromatin C
TAS
SceS000004897
GO:0003677 DNA binding F
IDA
DmeFBgn0011774
ISS
DmeFBgn0011774
NAS
DmeFBgn0011774
HsaP12956
GO:0003684 damaged DNA binding F
TAS
SceS000004897
GO:0003690 double-stranded DNA binding F
TAS
HsaP12956
GO:0003723 RNA binding F
IDA
SceS000004897
GO:0004003 ATP-dependent DNA helicase activity F
ISS
SpoSPCC126.02c
NAS
DmeFBgn0011774
TAS
HsaP12956
GO:0004677 DNA-dependent protein kinase activity F
IDA
DmeFBgn0011774
ISS
DmeFBgn0011774
NAS
DmeFBgn0011774
GO:0005515 protein binding F
IPI
HsaP12956
GO:0042162 telomeric DNA binding F
IDA
SpoSPCC126.02c
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC126.02c
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPCC126.02c
GO:0000723 telomere maintenance P
IMP
DmeFBgn0011774
SceS000004897
SpoSPCC126.02c
GO:0000724 double-strand break repair via homologous
recombination
P
IMP
SceS000004897
GO:0006266 DNA ligation P
TAS
HsaP12956
GO:0006303 double-strand break repair via nonhomologous end
joining
P
IDA
SceS000004897
IMP
SpoSPCC126.02c
TAS
HsaP12956
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000004897
GO:0006342 chromatin silencing P
IDA
SceS000004897
IMP
SceS000004897
GO:0008150 biological_process P
ND
HsaP12956
GO:0008340 determination of adult life span P
IMP
CelWBGene00000519
GO:0045893 positive regulation of transcription,
DNA-dependent
P
IDA
HsaP12956

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000004897

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000004897
(YMR284W)
Canis familiaris (Cfa) 1751 1 ENSCAFP00000001473
Gallus gallus (Gga) 1534 1 ENSGALP00000019436
(XRCC6)
O93257
Homo sapiens (Hsa) 1890 1 ENSP00000352257
(XRCC6)
Homo sapiens (Hsa) 1890 0.478 ENSP00000341536
Mus musculus (EMM) 1732 1 ENSMUSP00000023108
(MGI:95606)
P23475
Pan troglodytes (Ptr) 1714 1 ENSPTRP00000024862
Pan troglodytes (Ptr) 1714 0.859 ENSPTRP00000038524
Pan troglodytes (Ptr) 1714 0.347 ENSPTRP00000004822
Rattus norvegicus (ERN) 1723 1 ENSRNOP00000008819
(RGD:2643)
Q8VIB1
Dictyostelium discoideum (Ddi) 1836 1 DDB0186801
Mus musculus (Mmu) 1688 1 MGI:95606 P23475
Oryza sativa (Osa) 1668 1 Q7F1M0 Q7F1M0
Oryza sativa (Osa) 1668 0.509 Q7F1L9 Q7F1L9
Rattus norvegicus (Rno) 1525 1 RGD:2643 36380
Schizosaccharomyces pombe (Spo) 2459 1 SPCC126.02c O94395
Arabidopsis thaliana (Ath) 1751 1 NP_564012
(At1g16970.1)
Q9FQ08


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPCC126.02c
GO:0000790 nuclear chromatin C
TAS
SceS000004897
GO:0005624 membrane fraction C
ISS
RnoRGD:2643
GO:0005634 nucleus C
IDA
MmuMGI:95606
RnoRGD:2643
SpoSPCC126.02c
ISS
RnoRGD:2643
GO:0005635 nuclear envelope C
IDA
SceS000004897
GO:0005667 transcription factor complex C
ISS
RnoRGD:2643
GO:0005724 nuclear telomeric heterochromatin C
TAS
SceS000004897
GO:0005737 cytoplasm C
IDA
MmuMGI:95606
ISS
RnoRGD:2643
GO:0003684 damaged DNA binding F
TAS
SceS000004897
GO:0003690 double-stranded DNA binding F
ISS
RnoRGD:2643
GO:0003723 RNA binding F
IDA
SceS000004897
GO:0004003 ATP-dependent DNA helicase activity F
ISS
RnoRGD:2643
SpoSPCC126.02c
GO:0005515 protein binding F
ISS
RnoRGD:2643
GO:0042162 telomeric DNA binding F
IDA
SpoSPCC126.02c
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC126.02c
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPCC126.02c
GO:0000723 telomere maintenance P
IMP
SceS000004897
SpoSPCC126.02c
GO:0000724 double-strand break repair via homologous
recombination
P
IMP
SceS000004897
GO:0006266 DNA ligation P
ISS
RnoRGD:2643
GO:0006302 double-strand break repair P
IMP
MmuMGI:95606
ISS
RnoRGD:2643
TAS
RnoRGD:2643
GO:0006303 double-strand break repair via nonhomologous end
joining
P
IDA
SceS000004897
IMP
MmuMGI:95606
SpoSPCC126.02c
ISS
RnoRGD:2643
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000004897
GO:0006342 chromatin silencing P
IDA
SceS000004897
IMP
SceS000004897
GO:0045893 positive regulation of transcription,
DNA-dependent
P
ISS
RnoRGD:2643

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37483

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) XRCC6 GI:4503841 P12956
Pan troglodytes (Ptr) XRCC6 GI:114686702
Canis familiaris (Cfa) LOC474485 GI:57092715
Mus musculus (Mmu) Xrcc6
(MGI:95606)
GI:6753928 P23475
Rattus norvegicus (Rno) Xrcc6
(RGD:2643)
GI:21717799 36380
Gallus gallus (Gga) KU70 GI:45382537
Drosophila melanogaster (Dme) Irbp
(FBgn0011774)
GI:17985997 Q23976
Anopheles gambiae (Aga) ENSANGG00000008361 GI:58382869 Q7QCL6
Caenorhabditis elegans (Cel) cku-70
(CE28984;
WBGene00000519)
GI:17555930 Q9U2D2
Schizosaccharomyces pombe (Spo) SPCC126.02c GI:19075945 O94395
Saccharomyces cerevisiae (Sce) YKU70
(S000004897)
GI:6323940 P32807
Kluyveromyces lactis (Kla) KLLA0C06226g GI:50305035 Q6CUB4
Magnaporthe grisea (Mgr) MG01512.4 GI:39951739
Neurospora crassa (Ncr) GeneID:2710875 GI:32417036
Arabidopsis thaliana (Ath) KU70 GI:18394425 Q9FQ08
Oryza sativa (Osa) OJ1046_F10.128-1 GI:50934747


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPCC126.02c
GO:0000790 nuclear chromatin C
TAS
SceS000004897
GO:0005575 cellular_component C
ND
HsaP12956
GO:0005624 membrane fraction C
ISS
RnoRGD:2643
TAS
HsaP12956
GO:0005634 nucleus C
IDA
MmuMGI:95606
RnoRGD:2643
SpoSPCC126.02c
ISS
RnoRGD:2643
NAS
DmeFBgn0011774
TAS
HsaP12956
GO:0005635 nuclear envelope C
IDA
SceS000004897
GO:0005667 transcription factor complex C
IDA
HsaP12956
ISS
RnoRGD:2643
GO:0005724 nuclear telomeric heterochromatin C
TAS
SceS000004897
GO:0005737 cytoplasm C
IDA
MmuMGI:95606
ISS
RnoRGD:2643
GO:0003677 DNA binding F
IDA
DmeFBgn0011774
ISS
DmeFBgn0011774
NAS
DmeFBgn0011774
HsaP12956
GO:0003684 damaged DNA binding F
TAS
SceS000004897
GO:0003690 double-stranded DNA binding F
IDA
AthKU70
ISS
RnoRGD:2643
TAS
HsaP12956
GO:0003723 RNA binding F
IDA
SceS000004897
GO:0004003 ATP-dependent DNA helicase activity F
ISS
RnoRGD:2643
SpoSPCC126.02c
NAS
DmeFBgn0011774
TAS
HsaP12956
GO:0004677 DNA-dependent protein kinase activity F
IDA
DmeFBgn0011774
ISS
DmeFBgn0011774
NAS
DmeFBgn0011774
GO:0005515 protein binding F
IPI
AthKU70
HsaP12956
ISS
RnoRGD:2643
GO:0042162 telomeric DNA binding F
IDA
SpoSPCC126.02c
GO:0046982 protein heterodimerization activity F
IPI
SpoSPCC126.02c
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPCC126.02c
GO:0000723 telomere maintenance P
IMP
DmeFBgn0011774
SceS000004897
SpoSPCC126.02c
TAS
AthKU70
GO:0000724 double-strand break repair via homologous
recombination
P
IMP
SceS000004897
GO:0006266 DNA ligation P
ISS
RnoRGD:2643
TAS
HsaP12956
GO:0006281 DNA repair P
TAS
AthKU70
GO:0006302 double-strand break repair P
IMP
MmuMGI:95606
ISS
RnoRGD:2643
TAS
RnoRGD:2643
GO:0006303 double-strand break repair via nonhomologous end
joining
P
IDA
SceS000004897
IMP
MmuMGI:95606
SpoSPCC126.02c
ISS
RnoRGD:2643
TAS
HsaP12956
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000004897
GO:0006342 chromatin silencing P
IDA
SceS000004897
IMP
SceS000004897
GO:0008150 biological_process P
ND
HsaP12956
GO:0008340 determination of adult life span P
IMP
CelWBGene00000519
GO:0045893 positive regulation of transcription,
DNA-dependent
P
IDA
HsaP12956
ISS
RnoRGD:2643

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3087

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga4911 ENSANGP00000010850
Ashbya gossypii (Ago) ago475 ABL117C
Ashbya gossypii (Ago) ago3635 AFR443C
Arabidopsis thaliana (Ath) ath1815 At1g16970.1
Caenorhabditis elegans (Cel) cel19077 Y47D3A.4
(CE28984;
WBGene00000519)
Candida glabrata (Cgl) cgl2637 CAGL0I02662g
Cryptococcus neoformans (Cne) cne429 162.m04563
Dictyostelium discoideum (Ddi) ddi9269 DDB0186801
Debaryomyces hansenii (Dha) dha4878 DEHA0F11165g
Drosophila melanogaster (Dme) dme12032 CG5247-PA
(FBgn0011774)
Danio rerio (Dre) dre3350 ENSDARP00000006156
Takifugu rubripes (Fru) fru26206 SINFRUP00000149116
Gallus gallus (Gga) gga815 ENSGALP00000019436
(XRCC6)
O93257
Homo sapiens (Hsa) hsa21751 ENSP00000352257
(XRCC6)
Homo sapiens (Hsa) hsa21752 ENSP00000353192
(XRCC6)
P12956
Kluyveromyces lactis (Kla) kla1474 KLLA0C06226g
Mus musculus (Mmu) mmu9374 ENSMUSP00000023108
(MGI:95606)
P23475
Mus musculus (Mmu) mmu9375 ENSMUSP00000068559
(MGI:95606)
P23475
Neurospora crassa (Ncr) ncr8079 NCU08290.2
Oryza sativa (Osa) osa69168 6926.m00152
Oryza sativa (Osa) osa69172 6926.m00154
Rattus norvegicus (Rno) rno27467 ENSRNOP00000008819
(RGD:2643)
Q8VIB1
Saccharomyces cerevisiae (Sce) sce5058 YMR284W
(S000004897)
Schizosaccharomyces pombe (Spo) spo250 SPCC126.02c O94395
Yarrowia lipolytica (Yli) yli2073 YALI0C08701g