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Search term: YLR442C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SIR3
SGD link S000004434
Alternative ID YLR442C
Description Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p
Synonyms YLR442C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1514 ACDHYPE

KOGs classification KOGs description
L
INFORMATION STORAGE AND PROCESSING
Replication, recombination and repair
Origin recognition complex, subunit 1, and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g12620 GI:15235420 Q9SU24
Arabidopsis thaliana (Ath) At4g14700 GI:7488165
Caenorhabditis elegans (Cel) CE19131
(WBGene00012650)
GI:17555708 Q9XX17
Drosophila melanogaster (Dme) 7304200
(FBgn0022772)
GI:17137456 O16810
Homo sapiens (Hsa) Hs22057349 GI:22057349
Homo sapiens (Hsa) Hs4758850 GI:4758850
Saccharomyces cerevisiae (Sce) YLR442c
(S000004434)
GI:6323475 P06701
Saccharomyces cerevisiae (Sce) YML065w
(S000004530)
GI:6323575 P54784
Schizosaccharomyces pombe (Spo) SPBC29A10.15 GI:19112852 P54789
Encephalitozoon cuniculi (Ecu) ECU03g1030 GI:19173061 Q8SS92


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000783 nuclear telomere cap complex C
IDA
SceS000004434
GO:0000790 nuclear chromatin C
IDA
SpoSPBC29A10.15
GO:0000808 origin recognition complex C
ISS
AthAt4g12620
GO:0005634 nucleus C
IDA
SpoSPBC29A10.15
NAS
DmeFBgn0022772
RCA
AthAt4g12620
GO:0005656 pre-replicative complex C
IC
SpoSPBC29A10.15
TAS
SceS000004530
GO:0005657 replication fork C
IC
SpoSPBC29A10.15
GO:0005664 nuclear origin of replication recognition
complex
C
IDA
DmeFBgn0022772
SpoSPBC29A10.15
ISS
DmeFBgn0022772
NAS
DmeFBgn0022772
TAS
SceS000004530
GO:0005677 chromatin silencing complex C
IDA
SceS000004434
GO:0005724 nuclear telomeric heterochromatin C
IDA
SceS000004434
GO:0005730 nucleolus C
IDA
SceS000004434
GO:0005739 mitochondrion C
IDA
SceS000004434
GO:0003677 DNA binding F
NAS
DmeFBgn0022772
RCA
AthAt4g12620
GO:0003688 DNA replication origin binding F
IDA
SpoSPBC29A10.15
TAS
SceS000004530
GO:0005515 protein binding F
IPI
AthAt4g12620
GO:0005524 ATP binding F
ISS
SpoSPBC29A10.15
GO:0016887 ATPase activity F
ISS
SpoSPBC29A10.15
TAS
SceS000004530
GO:0030527 structural constituent of chromatin F
TAS
SceS000004434
GO:0042393 histone binding F
TAS
SceS000004434
GO:0000003 reproduction P
IMP
CelWBGene00012650
GO:0000076 DNA replication checkpoint P
IMP
SpoSPBC29A10.15
GO:0001308 loss of chromatin silencing during replicative
cell aging
P
IDA
SceS000004434
GO:0006260 DNA replication P
ISS
AthAt4g12620
RCA
AthAt4g12620
GO:0006261 DNA-dependent DNA replication P
ISS
DmeFBgn0022772
NAS
DmeFBgn0022772
GO:0006267 pre-replicative complex formation and
maintenance
P
TAS
SceS000004530
GO:0006270 DNA replication initiation P
IC
SpoSPBC29A10.15
IDA
DmeFBgn0022772
TAS
SceS000004530
GO:0006303 double-strand break repair via nonhomologous end
joining
P
IDA
SceS000004434
GO:0006342 chromatin silencing P
NAS
DmeFBgn0022772
TAS
SceS000004434
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00012650
GO:0030466 chromatin silencing at silent mating-type
cassette
P
TAS
SceS000004530

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000004434

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000004434
(YLR442C)
Saccharomyces cerevisiae (Sce) 1125 1 S000004530
(YML065W)
Canis familiaris (Cfa) 941 1 ENSCAFP00000005581
Saccharomyces cerevisiae (Sce) 941 1 S000004530
(YML065W)
Danio rerio (Dre) 772 1 ENSDARP00000018115
Saccharomyces cerevisiae (Sce) 772 1 S000004530
(YML065W)
Saccharomyces cerevisiae (Sce) 1088 1 S000004530
(YML065W)
Saccharomyces cerevisiae (Sce) 1126 1 S000004530
(YML065W)
Caenorhabditis elegans (Cel) 1126 1 WBGene00012650
(CE19131)
Dictyostelium discoideum (Ddi) 1072 1 DDB0218435
Saccharomyces cerevisiae (Sce) 1072 1 S000004530
(YML065W)
Saccharomyces cerevisiae (Sce) 1387 1 S000004530
(YML065W)
Schizosaccharomyces pombe (Spo) 1387 1 SPBC29A10.15 P54789


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000783 nuclear telomere cap complex C
IDA
SceS000004434
GO:0000790 nuclear chromatin C
IDA
SpoSPBC29A10.15
GO:0005634 nucleus C
IDA
SpoSPBC29A10.15
GO:0005656 pre-replicative complex C
IC
SpoSPBC29A10.15
TAS
SceS000004530
GO:0005657 replication fork C
IC
SpoSPBC29A10.15
GO:0005664 nuclear origin of replication recognition
complex
C
IDA
SpoSPBC29A10.15
TAS
SceS000004530
GO:0005677 chromatin silencing complex C
IDA
SceS000004434
GO:0005724 nuclear telomeric heterochromatin C
IDA
SceS000004434
GO:0005730 nucleolus C
IDA
SceS000004434
GO:0005739 mitochondrion C
IDA
SceS000004434
GO:0003688 DNA replication origin binding F
IDA
SpoSPBC29A10.15
TAS
SceS000004530
GO:0005524 ATP binding F
ISS
SpoSPBC29A10.15
GO:0016887 ATPase activity F
ISS
SpoSPBC29A10.15
TAS
SceS000004530
GO:0030527 structural constituent of chromatin F
TAS
SceS000004434
GO:0042393 histone binding F
TAS
SceS000004434
GO:0000003 reproduction P
IMP
CelWBGene00012650
GO:0000076 DNA replication checkpoint P
IMP
SpoSPBC29A10.15
GO:0001308 loss of chromatin silencing during replicative
cell aging
P
IDA
SceS000004434
GO:0006267 pre-replicative complex formation and
maintenance
P
TAS
SceS000004530
GO:0006270 DNA replication initiation P
IC
SpoSPBC29A10.15
TAS
SceS000004530
GO:0006303 double-strand break repair via nonhomologous end
joining
P
IDA
SceS000004434
GO:0006342 chromatin silencing P
TAS
SceS000004434
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00012650
GO:0030466 chromatin silencing at silent mating-type
cassette
P
TAS
SceS000004530

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk