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Search term: YLR058C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SHM2
SGD link S000004048
Alternative ID YLR058C
Description Cytosolic serine hydroxymethyltransferase, involved in one-carbon metabolism
Synonyms YLR058C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2467 ACDHYPE

KOGs classification KOGs description
E
METABOLISM
Amino acid transport and metabolism
Glycine/serine hydroxymethyltransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g22020 GI:15219182 Q9LM59
Arabidopsis thaliana (Ath) At1g36370 GI:12324475
Arabidopsis thaliana (Ath) At4g13890 GI:15236371 Q9SVM4
Arabidopsis thaliana (Ath) At4g13930 GI:15236375 O23254
Arabidopsis thaliana (Ath) At4g32520 GI:7433550
Arabidopsis thaliana (Ath) At4g37930 GI:15235745 Q9SZJ5
Arabidopsis thaliana (Ath) At5g26780 GI:7433553
Caenorhabditis elegans (Cel) CE01130
(WBGene00003214)
GI:17554316 P50432
Drosophila melanogaster (Dme) 7290652 GI:7290652 Q9W457
Homo sapiens (Hsa) Hs19923315
(SHMT2)
GI:19923315 P34897
Homo sapiens (Hsa) Hs20070176 GI:20070176
Saccharomyces cerevisiae (Sce) YBR263w
(S000000467)
GI:6319739
Saccharomyces cerevisiae (Sce) YLR058c
(S000004048)
GI:6323087 P37291
Schizosaccharomyces pombe (Spo) SPAC18G6.04c GI:19114580 Q10104
Schizosaccharomyces pombe (Spo) SPAC24C9.12c GI:19114949 O13972
Encephalitozoon cuniculi (Ecu) ECU01g0190 GI:19075029
Encephalitozoon cuniculi (Ecu) ECU01g1420 GI:19075029


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt1g22020
GO:0005737 cytoplasm C
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0005739 mitochondrion C
IDA
SceS000000467
SpoSPAC18G6.04c
ISS
SpoSPAC18G6.04c
TAS
HsaP34897
SceS000000467
GO:0005829 cytosol C
ISS
AthAt4g13930
GO:0004372 glycine hydroxymethyltransferase
activity
F
ISS
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt5g26780
At4g13930
At4g32520
At1g36370
At1g22020
TAS
SceS000004048
S000000467
GO:0006544 glycine metabolism P
ISS
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt1g22020
At1g36370
At4g32520
At5g26780
At4g13930
GO:0006563 L-serine metabolism P
ISS
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt4g13930
At5g26780
At4g32520
At1g22020
At1g36370
GO:0006730 one-carbon compound metabolism P
IC
SpoSPAC18G6.04c
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
S000000467
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00003214

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000004048

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000004048
(YLR058C)
Anopheles gambiae (Aga) 192 1 ENSANGP00000022109
Saccharomyces cerevisiae (Sce) 192 0.083 S000000467
(YBR263W)
Saccharomyces cerevisiae (Sce) 113 0.124 S000000467
(YBR263W)
Canis familiaris (Cfa) 188 1 ENSCAFP00000026966
Canis familiaris (Cfa) 188 0.166 ENSCAFP00000000282
Saccharomyces cerevisiae (Sce) 192 0.077 S000000467
(YBR263W)
Danio rerio (Dre) 129 1 ENSDARP00000004022
Saccharomyces cerevisiae (Sce) 201 1 S000000467
(YBR263W)
Takifugu rubripes (Fru) 201 1 SINFRUP00000160470
Takifugu rubripes (Fru) 201 1 SINFRUP00000171194
Gallus gallus (Gga) 165 1 ENSGALP00000008079
(LOC416520)
Homo sapiens (Hsa) 202 1 ENSP00000318868
(SHMT1)
P34896-1
Homo sapiens (Hsa) 202 0.178 ENSP00000333667
(SHMT2)
P34897
Mus musculus (EMM) 179 1 ENSMUSP00000018744
(MGI:98299)
Q8R0X9
Mus musculus (EMM) 179 0.153 ENSMUSP00000026470
(MGI:1277989)
Q99K87
Pan troglodytes (Ptr) 145 1 ENSPTRP00000015094
Pan troglodytes (Ptr) 145 0.124 ENSPTRP00000008712
Rattus norvegicus (ERN) 176 1 ENSRNOP00000007092
(RGD:1312011)
Q6TXG7
Rattus norvegicus (ERN) 176 0.155 ENSRNOP00000011082
(RGD:1308582)
Q5U3Z7
Saccharomyces cerevisiae (Sce) 172 0.077 S000000467
(YBR263W)
Caenorhabditis elegans (Cel) 160 1 WBGene00003214
(CE01130)
P50432
Dictyostelium discoideum (Ddi) 251 1 DDB0230072
Dictyostelium discoideum (Ddi) 251 0.389 DDB0230073
Saccharomyces cerevisiae (Sce) 251 0.164 S000000467
(YBR263W)
Drosophila melanogaster (Dme) 192 1 CG3011-PA
(FBgn0029823)
Saccharomyces cerevisiae (Sce) 192 0.077 S000000467
(YBR263W)
Saccharomyces cerevisiae (Sce) 170 0.108 S000000467
(YBR263W)
Mus musculus (Mmu) 179 1 MGI:98299 P50431
Mus musculus (Mmu) 179 0.14 MGI:1277989 Q3TFD0
Oryza sativa (Osa) 129 1 Q7Y1F0 Q7Y1F0
Oryza sativa (Osa) 129 0.58 Q6TUC6 Q6TUC6
Rattus norvegicus (Rno) 161 1 RGD:1312011
Schizosaccharomyces pombe (Spo) 264 1 SPAC24C9.12c O13972
Arabidopsis thaliana (Ath) 161 1 NP_195506
(At4g37930.1)
Q9SZJ5
Arabidopsis thaliana (Ath) 161 0.697 NP_851080
(At5g26780.1)
Arabidopsis thaliana (Ath) 161 0.679 NP_568488
(At5g26780.3)
Q8GRI1
Arabidopsis thaliana (Ath) 161 0.679 NP_851081
(At5g26780.2)
Escherichia coli (Eco) 63 1 NP_417046
(EG10408)
P0A825
Saccharomyces cerevisiae (Sce) 63 1 S000000467
(YBR263W)
Plasmodium falciparum (Pfa) 154 1 PFL1720w
Saccharomyces cerevisiae (Sce) 154 0.279 S000000467
(YBR263W)


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DdiDDB0230073
PfaPFL1720w
GO:0005737 cytoplasm C
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0005739 mitochondrion C
IDA
MmuMGI:1277989
MGI:98299
RnoRGD:1308582
SceS000000467
ISS
DmeFBgn0029823
RnoRGD:1312011
RGD:1308582
RCA
MmuMGI:1277989
TAS
HsaP34897
RnoRGD:1308582
SceS000000467
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1277989
ISS
RnoRGD:1308582
GO:0005829 cytosol C
ISS
RnoRGD:1312011
TAS
HsaP34896
RnoRGD:1312011
GO:0045335 phagocytic vesicle C
IDA
DdiDDB0230072
GO:0004372 glycine hydroxymethyltransferase
activity
F
IDA
RnoRGD:1308582
ISS
DdiDDB0230073
DDB0230072
DmeFBgn0029823
RnoRGD:1308582
SpoSPAC24C9.12c
RCA
AthAt5g26780
MmuMGI:1277989
TAS
RnoRGD:1312011
RGD:1308582
SceS000004048
S000000467
GO:0008168 methyltransferase activity F
ISS
RnoRGD:1308582
RCA
MmuMGI:1277989
GO:0030170 pyridoxal phosphate binding F
TAS
RnoRGD:1312011
RGD:1308582
GO:0006544 glycine metabolism P
ISS
SpoSPAC24C9.12c
RCA
AthAt5g26780
TAS
RnoRGD:1312011
RGD:1308582
GO:0006563 L-serine metabolism P
ISS
SpoSPAC24C9.12c
RCA
AthAt5g26780
TAS
RnoRGD:1312011
RGD:1308582
GO:0006564 L-serine biosynthesis P
ISS
DmeFBgn0029823
GO:0006565 L-serine catabolism P
ISS
RnoRGD:1312011
NR
HsaP34896
GO:0006730 one-carbon compound metabolism P
ISS
DdiDDB0230072
DDB0230073
SpoSPAC24C9.12c
TAS
PfaPFL1720w
SceS000004048
S000000467
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00003214

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
3074

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SHMT1 GI:22547186 P34896
Pan troglodytes (Ptr) SHMT1 GI:114668829
Canis familiaris (Cfa) LOC489536 GI:73956022
Mus musculus (Mmu) Shmt1
(MGI:98299)
GI:67846103 P50431
Rattus norvegicus (Rno) Shmt1
(RGD:1312011)
GI:62656183 Q6TXG7
Gallus gallus (Gga) LOC416520 GI:50755621
Drosophila melanogaster (Dme) CG3011
(FBgn0029823)
GI:24640005 Q9W457
Anopheles gambiae (Aga) ENSANGG00000019620 GI:58391072 Q7Q2F2
Caenorhabditis elegans (Cel) mel-32
(CE01130;
WBGene00003214)
GI:25144732 P50432
Schizosaccharomyces pombe (Spo) SPAC24C9.12c GI:19114949 O13972
Saccharomyces cerevisiae (Sce) SHM2
(S000004048)
GI:6323087 P37291
Kluyveromyces lactis (Kla) KLLA0F08921g GI:50310925 Q6CKQ4
Eremothecium gossypii (Ego) ACR215C GI:45185901
Magnaporthe grisea (Mgr) MG00923.4 GI:39973861
Neurospora crassa (Ncr) GeneID:2712946 GI:32421213
Arabidopsis thaliana (Ath) AT5G26780 GI:30690404 Q8GRI1


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0005739 mitochondrion C
IDA
MmuMGI:98299
ISS
DmeFBgn0029823
RnoRGD:1312011
GO:0005829 cytosol C
ISS
RnoRGD:1312011
TAS
HsaP34896
RnoRGD:1312011
GO:0004372 glycine hydroxymethyltransferase
activity
F
ISS
DmeFBgn0029823
SpoSPAC24C9.12c
RCA
AthAt5g26780
TAS
RnoRGD:1312011
SceS000004048
GO:0030170 pyridoxal phosphate binding F
TAS
RnoRGD:1312011
GO:0006544 glycine metabolism P
ISS
SpoSPAC24C9.12c
RCA
AthAt5g26780
TAS
RnoRGD:1312011
GO:0006563 L-serine metabolism P
ISS
SpoSPAC24C9.12c
RCA
AthAt5g26780
TAS
RnoRGD:1312011
GO:0006564 L-serine biosynthesis P
ISS
DmeFBgn0029823
GO:0006565 L-serine catabolism P
ISS
RnoRGD:1312011
NR
HsaP34896
GO:0006730 one-carbon compound metabolism P
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00003214

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_185

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga13205 ENSANGP00000000142
Anopheles gambiae (Aga) aga15784 ENSANGP00000022109
Ashbya gossypii (Ago) ago1262 ACR215C
Ashbya gossypii (Ago) ago2318 AEL188W
Arabidopsis thaliana (Ath) ath19158 At4g13890.1
Arabidopsis thaliana (Ath) ath19160 At4g13930.1
Arabidopsis thaliana (Ath) ath21349 At4g32520.1
Arabidopsis thaliana (Ath) ath21978 At4g37930.1
Arabidopsis thaliana (Ath) ath24948 At5g26780.1
Arabidopsis thaliana (Ath) ath24949 At5g26780.2
Arabidopsis thaliana (Ath) ath24950 At5g26780.3
Caenorhabditis elegans (Cel) cel1135 C05D11.11a
(CE01130;
WBGene00003214)
P50432
Caenorhabditis elegans (Cel) cel1136 C05D11.11b
(CE29661)
Candida glabrata (Cgl) cgl1306 CAGL0F01749g
Candida glabrata (Cgl) cgl2921 CAGL0I09284g
Cryptococcus neoformans (Cne) cne3808 185.m02385
Dictyostelium discoideum (Ddi) ddi12477 DDB0230072
Dictyostelium discoideum (Ddi) ddi13430 DDB0230073
Debaryomyces hansenii (Dha) dha2053 DEHA0C14113g
Debaryomyces hansenii (Dha) dha3553 DEHA0E07051g
Drosophila melanogaster (Dme) dme16655 CG3011-PA
(FBgn0029823)
Danio rerio (Dre) dre19924 ENSDARP00000004022
Escherichia coli (Eco) eco2472 16130476
(EG10408)
P0A825
Encephalitozoon cuniculi (Ecu) ecu1666 19075029
Encephalitozoon cuniculi (Ecu) ecu1792 19075155
Takifugu rubripes (Fru) fru28058 SINFRUP00000150265
Takifugu rubripes (Fru) fru14058 SINFRUP00000160470
Takifugu rubripes (Fru) fru28057 SINFRUP00000169730
Takifugu rubripes (Fru) fru28056 SINFRUP00000171194
Gallus gallus (Gga) gga6514 ENSGALP00000008079
(LOC416520)
Homo sapiens (Hsa) hsa13188 ENSP00000318805
(SHMT1)
P34896-2
Homo sapiens (Hsa) hsa13187 ENSP00000318868
(SHMT1)
P34896-1
Homo sapiens (Hsa) hsa7727 ENSP00000333667
(SHMT2)
P34897
Homo sapiens (Hsa) hsa13189 ENSP00000345881
(SHMT1)
P34896-3
Kluyveromyces lactis (Kla) kla4133 KLLA0F01210g
Kluyveromyces lactis (Kla) kla4485 KLLA0F08921g
Mus musculus (Mmu) mmu3849 ENSMUSP00000018744
(MGI:98299)
Q8R0X9
Mus musculus (Mmu) mmu2977 ENSMUSP00000026470
(MGI:1277989)
Q99K87
Mus musculus (Mmu) mmu24258 ENSMUSP00000072641
Mus musculus (Mmu) mmu24259 ENSMUSP00000075815
Neurospora crassa (Ncr) ncr2213 NCU02274.2
Neurospora crassa (Ncr) ncr5643 NCU05805.2
Oryza sativa (Osa) osa52657 6105.m00160
Oryza sativa (Osa) osa63606 6740.m00178
Oryza sativa (Osa) osa63627 6740.m00191
Oryza sativa (Osa) osa73909 7164.m00153
Oryza sativa (Osa) osa76833 7417.m00114
Plasmodium falciparum (Pfa) pfa5127 PFL1720w
Rattus norvegicus (Rno) rno5186 ENSRNOP00000007092
(RGD:1312011)
Q6TXG7
Rattus norvegicus (Rno) rno26907 ENSRNOP00000011082
(RGD:1308582)
Q5U3Z7
Saccharomyces cerevisiae (Sce) sce540 YBR263W
(S000000467)
Saccharomyces cerevisiae (Sce) sce4139 YLR058C
(S000004048)
Schizosaccharomyces pombe (Spo) spo3483 SPAC18G6.04c Q10104
Schizosaccharomyces pombe (Spo) spo1437 SPAC24C9.12c O13972
Yarrowia lipolytica (Yli) yli3647 YALI0D22484g
Yarrowia lipolytica (Yli) yli4533 YALI0E16346g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
DdiDDB0230073
PfaPFL1720w
GO:0005737 cytoplasm C
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0005739 mitochondrion C
IDA
MmuMGI:1277989
MGI:98299
RnoRGD:1308582
SceS000000467
SpoSPAC18G6.04c
ISS
DmeFBgn0029823
RnoRGD:1312011
RGD:1308582
SpoSPAC18G6.04c
RCA
MmuMGI:1277989
TAS
HsaP34897
RnoRGD:1308582
SceS000000467
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1277989
ISS
RnoRGD:1308582
GO:0005829 cytosol C
ISS
AthAt4g13930
RnoRGD:1312011
TAS
HsaP34896
RnoRGD:1312011
GO:0045335 phagocytic vesicle C
IDA
DdiDDB0230072
GO:0004372 glycine hydroxymethyltransferase
activity
F
IDA
RnoRGD:1308582
ISS
DdiDDB0230073
DDB0230072
DmeFBgn0029823
RnoRGD:1308582
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt5g26780
At4g13930
At4g32520
MmuMGI:1277989
TAS
RnoRGD:1312011
RGD:1308582
SceS000004048
S000000467
GO:0008168 methyltransferase activity F
ISS
RnoRGD:1308582
RCA
MmuMGI:1277989
GO:0030170 pyridoxal phosphate binding F
TAS
RnoRGD:1312011
RGD:1308582
GO:0006544 glycine metabolism P
ISS
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt4g32520
At5g26780
At4g13930
TAS
RnoRGD:1312011
RGD:1308582
GO:0006563 L-serine metabolism P
ISS
SpoSPAC24C9.12c
SPAC18G6.04c
RCA
AthAt4g13930
At5g26780
At4g32520
TAS
RnoRGD:1312011
RGD:1308582
GO:0006564 L-serine biosynthesis P
ISS
DmeFBgn0029823
GO:0006565 L-serine catabolism P
ISS
RnoRGD:1312011
NR
HsaP34896
GO:0006730 one-carbon compound metabolism P
IC
SpoSPAC18G6.04c
ISS
DdiDDB0230072
DDB0230073
SpoSPAC24C9.12c
TAS
PfaPFL1720w
SceS000004048
S000000467
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00003214

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPAC24C9.12c
(O13972)
YLR058C
(S000004048)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0004372 glycine hydroxymethyltransferase
activity
F
ISS
SpoSPAC24C9.12c
TAS
SceS000004048
GO:0006544 glycine metabolism P
ISS
SpoSPAC24C9.12c
GO:0006563 L-serine metabolism P
ISS
SpoSPAC24C9.12c
GO:0006730 one-carbon compound metabolism P
ISS
SpoSPAC24C9.12c
TAS
SceS000004048

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Query species:

Include wild-cards:   

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GO info in one table:

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