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Search term: YJL138C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIF2
SGD link S000003674
Alternative ID YJL138C
Description Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G
Synonyms YJL138C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0327 ACDHYPE

KOGs classification KOGs description
J
INFORMATION STORAGE AND PROCESSING
Translation, ribosomal structure and biogenesis
Translation initiation factor 4F, helicase subunit (eIF-4A) and related helicases

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g12690 GI:15222047
Arabidopsis thaliana (Ath) At1g12770_1 GI:15220990
Arabidopsis thaliana (Ath) At1g54270 GI:15221761 P41377
Arabidopsis thaliana (Ath) At1g72730 GI:15218574 Q9CAI7
Arabidopsis thaliana (Ath) At3g13920 GI:18400210 P41376
Arabidopsis thaliana (Ath) At5g19210 GI:15239683
Caenorhabditis elegans (Cel) CE01338
(WBGene00018997)
GI:17553716 Q20935
Caenorhabditis elegans (Cel) CE01341
(WBGene00002083)
GI:17553942 P27639
Drosophila melanogaster (Dme) 7297048 GI:7297048
Homo sapiens (Hsa) Hs17459025 GI:17459025
Homo sapiens (Hsa) Hs17475661 GI:17475661
Homo sapiens (Hsa) Hs17476177 GI:17476177
Homo sapiens (Hsa) Hs20479405 GI:20479405
Homo sapiens (Hsa) Hs20482355 GI:20482355
Homo sapiens (Hsa) Hs20538426_2 GI:20538426
Homo sapiens (Hsa) Hs20548087 GI:20548087
Homo sapiens (Hsa) Hs22057430 GI:22057430
Homo sapiens (Hsa) Hs4503529
(EIF4A1)
GI:4503529 Q9NZR9
Homo sapiens (Hsa) Hs4503531 GI:4503531
Homo sapiens (Hsa) Hs4826688 GI:4826688
Saccharomyces cerevisiae (Sce) YJL138c
(S000003674)
GI:6322323 P10081
Saccharomyces cerevisiae (Sce) YKR059w
(S000001767)
GI:6322323 P10081
Schizosaccharomyces pombe (Spo) SPAC1006.07 GI:19115766 P47943
Encephalitozoon cuniculi (Ecu) ECU09g1200 GI:19173239


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g13920
GO:0005737 cytoplasm C
IDA
SceS000003674
ISS
SceS000003674
GO:0005829 cytosol C
IDA
SpoSPAC1006.07
GO:0005840 ribosome C
TAS
SceS000001767
S000003674
GO:0016281 eukaryotic translation initiation factor 4F
complex
C
IGI
SceS000003674
S000001767
ISS
SceS000003674
S000001767
SpoSPAC1006.07
GO:0003724 RNA helicase activity F
IDA
SceS000003674
GO:0003743 translation initiation factor activity F
IDA
SceS000001767
S000003674
IMP
SceS000001767
ISS
AthAt3g13920
At1g54270
SceS000003674
SpoSPAC1006.07
TAS
SceS000003674
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000001767
IMP
SceS000001767
ISS
SpoSPAC1006.07
GO:0005524 ATP binding F
IC
SpoSPAC1006.07
GO:0008026 ATP-dependent helicase activity F
RCA
AthAt5g19210
At3g13920
GO:0000003 reproduction P
IMP
CelWBGene00018997
GO:0000723 telomere maintenance P
IMP
SceS000001767
GO:0006413 translational initiation P
IDA
SceS000001767
IMP
SceS000001767
ISS
AthAt3g13920
SpoSPAC1006.07
TAS
SceS000003674
GO:0006446 regulation of translational initiation P
ISS
SceS000003674
GO:0007626 locomotory behavior P
IMP
CelWBGene00018997
WBGene00002083
GO:0008150 biological_process P
ND
AthAt5g19210
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00018997
WBGene00002083
GO:0040007 growth P
IMP
CelWBGene00002083
WBGene00018997

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000003674

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000003674
(YJL138C)
Anopheles gambiae (Aga) 205 1 ENSANGP00000020417
Saccharomyces cerevisiae (Sce) 205 1 S000001767
(YKR059W)
Anopheles gambiae (Aga) 205 0.112 ENSANGP00000014802
Saccharomyces cerevisiae (Sce) 182 1 S000001767
(YKR059W)
Canis familiaris (Cfa) 206 1 ENSCAFP00000024479
Saccharomyces cerevisiae (Sce) 206 1 S000001767
(YKR059W)
Canis familiaris (Cfa) 206 0.786 ENSCAFP00000020138
Saccharomyces cerevisiae (Sce) 199 1 S000001767
(YKR059W)
Danio rerio (Dre) 153 1 ENSDARP00000040225
Danio rerio (Dre) 153 1 ENSDARP00000042150
Saccharomyces cerevisiae (Sce) 153 1 S000001767
(YKR059W)
Danio rerio (Dre) 153 0.851 ENSDARP00000018923
(eif4a1b)
Q7ZU67
Saccharomyces cerevisiae (Sce) 204 1 S000001767
(YKR059W)
Takifugu rubripes (Fru) 204 1 SINFRUP00000139907
Takifugu rubripes (Fru) 204 0.449 SINFRUP00000141871
Gallus gallus (Gga) 187 1 ENSGALP00000014119
(EIF4A2)
Q8JFP1
Saccharomyces cerevisiae (Sce) 187 1 S000001767
(YKR059W)
Homo sapiens (Hsa) 222 1 ENSP00000293831
(EIF4A1)
P60842
Saccharomyces cerevisiae (Sce) 222 1 S000001767
(YKR059W)
Homo sapiens (Hsa) 222 0.783 ENSP00000326381
(EIF4A2)
Q14240-1
Homo sapiens (Hsa) 222 0.734 ENSP00000309842
Homo sapiens (Hsa) 222 0.331 ENSP00000335721
Mus musculus (EMM) 209 1 ENSMUSP00000018919
Saccharomyces cerevisiae (Sce) 209 1 S000001767
(YKR059W)
Mus musculus (EMM) 209 0.997 ENSMUSP00000074886
Mus musculus (EMM) 209 0.852 ENSMUSP00000072748
(GI:433225)
Mus musculus (EMM) 209 0.786 ENSMUSP00000023599
(MGI:106906)
P10630-1
Pan troglodytes (Ptr) 169 1 ENSPTRP00000014825
Saccharomyces cerevisiae (Sce) 169 1 S000001767
(YKR059W)
Pan troglodytes (Ptr) 169 0.775 ENSPTRP00000027042
Rattus norvegicus (ERN) 204 1 ENSRNOP00000018026
Saccharomyces cerevisiae (Sce) 204 1 S000001767
(YKR059W)
Rattus norvegicus (ERN) 204 0.804 ENSRNOP00000002484
(RGD:1309225)
Q5RKI1
Saccharomyces cerevisiae (Sce) 209 1 S000001767
(YKR059W)
Saccharomyces cerevisiae (Sce) 177 1 S000001767
(YKR059W)
Saccharomyces cerevisiae (Sce) 182 1 S000001767
(YKR059W)
Caenorhabditis elegans (Cel) 182 1 WBGene00002083
(CE01341)
P27639
Dictyostelium discoideum (Ddi) 249 1 DDB0191262
Saccharomyces cerevisiae (Sce) 249 1 S000001767
(YKR059W)
Drosophila melanogaster (Dme) 198 1 CG9075-PA
(FBgn0001942)
Saccharomyces cerevisiae (Sce) 198 1 S000001767
(YKR059W)
Saccharomyces cerevisiae (Sce) 175 1 S000001767
(YKR059W)
Mus musculus (Mmu) 210 1 MGI:95303 P60843
Saccharomyces cerevisiae (Sce) 210 1 S000001767
(YKR059W)
Mus musculus (Mmu) 210 0.783 MGI:106906 P10630
Oryza sativa (Osa) 179 1 Q6Z2Z4 Q6Z2Z4
Saccharomyces cerevisiae (Sce) 179 1 S000001767
(YKR059W)
Oryza sativa (Osa) 179 0.909 P35683 P35683
Oryza sativa (Osa) 179 0.842 Q9AR32 Q9AR32
Rattus norvegicus (Rno) 181 1 RGD:735141
Saccharomyces cerevisiae (Sce) 181 1 S000001767
(YKR059W)
Saccharomyces cerevisiae (Sce) 365 1 S000001767
(YKR059W)
Schizosaccharomyces pombe (Spo) 365 1 SPAC1006.07 P47943
Arabidopsis thaliana (Ath) 212 1 NP_566469
(At3g13920.1)
P41376
Saccharomyces cerevisiae (Sce) 212 1 S000001767
(YKR059W)
Arabidopsis thaliana (Ath) 212 0.93 NP_175829
(At1g54270.1)
P41377
Arabidopsis thaliana (Ath) 212 0.782 NP_177417
(At1g72730.1)
Q9CAI7
Plasmodium falciparum (Pfa) 112 1 PF14_0655
Saccharomyces cerevisiae (Sce) 112 1 S000001767
(YKR059W)


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g13920
GO:0005634 nucleus C
IC
DmeFBgn0001942
GO:0005737 cytoplasm C
IDA
SceS000003674
ISS
SceS000003674
GO:0005829 cytosol C
IDA
SpoSPAC1006.07
ISS
DmeFBgn0001942
NAS
DmeFBgn0001942
GO:0005840 ribosome C
TAS
SceS000001767
S000003674
GO:0016281 eukaryotic translation initiation factor 4F
complex
C
IGI
SceS000003674
S000001767
ISS
DmeFBgn0001942
PfaPF14_0655
RnoRGD:1309225
SceS000003674
S000001767
SpoSPAC1006.07
TAS
HsaQ14240
GO:0045335 phagocytic vesicle C
IDA
DdiDDB0191262
GO:0000339 RNA cap binding F
ISS
PfaPF14_0655
NAS
DmeFBgn0001942
GO:0003676 nucleic acid binding F
RCA
OsaQ9AR32
P35683
GO:0003724 RNA helicase activity F
IDA
SceS000003674
ISS
DmeFBgn0001942
GO:0003729 mRNA binding F
ISS
PfaPF14_0655
NAS
DmeFBgn0001942
GO:0003743 translation initiation factor activity F
IDA
SceS000001767
S000003674
IMP
SceS000001767
ISS
AthAt3g13920
At1g54270
DmeFBgn0001942
PfaPF14_0655
RnoRGD:1309225
RGD:735141
SceS000003674
SpoSPAC1006.07
NAS
DmeFBgn0001942
TAS
HsaQ14240
SceS000003674
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000001767
IMP
SceS000001767
ISS
SpoSPAC1006.07
GO:0004386 helicase activity F
RCA
OsaP35683
Q9AR32
GO:0005515 protein binding F
IPI
HsaQ14240
P60842
ISS
RnoRGD:1309225
GO:0005524 ATP binding F
IC
SpoSPAC1006.07
RCA
OsaP35683
Q9AR32
GO:0008026 ATP-dependent helicase activity F
RCA
AthAt3g13920
OsaP35683
Q9AR32
GO:0017116 single-stranded DNA-dependent ATP-dependent DNA
helicase activity
F
NAS
DmeFBgn0001942
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome
P
IMP
DmeFBgn0001942
GO:0000723 telomere maintenance P
IMP
SceS000001767
GO:0002168 larval development (sensu Insecta) P
TAS
DmeFBgn0001942
GO:0006268 DNA unwinding during replication P
NAS
DmeFBgn0001942
GO:0006413 translational initiation P
IDA
SceS000001767
IMP
SceS000001767
ISS
AthAt3g13920
DmeFBgn0001942
RnoRGD:735141
SpoSPAC1006.07
NAS
DmeFBgn0001942
TAS
SceS000003674
GO:0006446 regulation of translational initiation P
ISS
PfaPF14_0655
RnoRGD:1309225
SceS000003674
TAS
HsaQ14240
GO:0007446 imaginal disc growth P
TAS
DmeFBgn0001942
GO:0007626 locomotory behavior P
IMP
CelWBGene00002083
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00002083
GO:0009950 dorsal/ventral axis specification P
IMP
DmeFBgn0001942
GO:0040007 growth P
IMP
CelWBGene00002083

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1487

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EIF4A2 GI:83700235 Q9NZE6
Pan troglodytes (Ptr) LOC460917 GI:55621670
Canis familiaris (Cfa) LOC488118 GI:74003468
Mus musculus (Mmu) Eif4a2
(MGI:106906)
GI:7305019 P10630
Rattus norvegicus (Rno) Eif4a2
(RGD:1309225)
GI:56605748 O08772
Gallus gallus (Gga) EIF4AII GI:45383077
Drosophila melanogaster (Dme) eIF-4a
(FBgn0001942)
GI:24582078 Q02748
Anopheles gambiae (Aga) ENSANGG00000012313 GI:58429104 Q7Q1C1
Caenorhabditis elegans (Cel) inf-1
(CE01341;
WBGene00002083)
GI:71987143 P27639
Schizosaccharomyces pombe (Spo) tif1
(SPAC1006.07)
GI:19115766 P47943
Saccharomyces cerevisiae (Sce) TIF2
(S000003674)
GI:6322323 P10081
Saccharomyces cerevisiae (Sce) TIF1
(S000001767)
GI:6322912 P10081
Kluyveromyces lactis (Kla) KLLA0A05731g GI:50302639 Q6CXT4
Eremothecium gossypii (Ego) ACR253C GI:45185939
Magnaporthe grisea (Mgr) MG04400.4 GI:39944836
Neurospora crassa (Ncr) GeneID:2709537 GI:32414453
Arabidopsis thaliana (Ath) EIF4A-2 GI:15221761 P41377


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
DmeFBgn0001942
GO:0005737 cytoplasm C
IDA
SceS000003674
ISS
SceS000003674
GO:0005829 cytosol C
IDA
SpoSPAC1006.07
ISS
DmeFBgn0001942
NAS
DmeFBgn0001942
GO:0005840 ribosome C
TAS
SceS000001767
S000003674
GO:0016281 eukaryotic translation initiation factor 4F
complex
C
IGI
SceS000003674
S000001767
ISS
DmeFBgn0001942
RnoRGD:1309225
SceS000003674
S000001767
SpoSPAC1006.07
GO:0000339 RNA cap binding F
NAS
DmeFBgn0001942
GO:0003724 RNA helicase activity F
IDA
SceS000003674
ISS
DmeFBgn0001942
GO:0003729 mRNA binding F
NAS
DmeFBgn0001942
GO:0003743 translation initiation factor activity F
IDA
SceS000001767
S000003674
IMP
SceS000001767
ISS
AthEIF4A-2
DmeFBgn0001942
RnoRGD:1309225
SceS000003674
SpoSPAC1006.07
NAS
DmeFBgn0001942
TAS
SceS000003674
GO:0004004 ATP-dependent RNA helicase activity F
IDA
SceS000001767
IMP
SceS000001767
ISS
SpoSPAC1006.07
GO:0005515 protein binding F
ISS
RnoRGD:1309225
GO:0005524 ATP binding F
IC
SpoSPAC1006.07
GO:0017116 single-stranded DNA-dependent ATP-dependent DNA
helicase activity
F
NAS
DmeFBgn0001942
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome
P
IMP
DmeFBgn0001942
GO:0000723 telomere maintenance P
IMP
SceS000001767
GO:0002168 larval development (sensu Insecta) P
TAS
DmeFBgn0001942
GO:0006268 DNA unwinding during replication P
NAS
DmeFBgn0001942
GO:0006413 translational initiation P
IDA
SceS000001767
IMP
SceS000001767
ISS
DmeFBgn0001942
SpoSPAC1006.07
NAS
DmeFBgn0001942
TAS
SceS000003674
GO:0006446 regulation of translational initiation P
ISS
RnoRGD:1309225
SceS000003674
GO:0007446 imaginal disc growth P
TAS
DmeFBgn0001942
GO:0007626 locomotory behavior P
IMP
CelWBGene00002083
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00002083
GO:0009950 dorsal/ventral axis specification P
IMP
DmeFBgn0001942