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Search term: YJL026W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RNR2
SGD link S000003563
Alternative ID YJL026W
Description Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits
Synonyms YJL026W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1567 ACDHYPE

KOGs classification KOGs description
F
METABOLISM
Nucleotide transport and metabolism
Ribonucleotide reductase, beta subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g23580 GI:15229476 P50651
Arabidopsis thaliana (Ath) At3g27060 GI:15232077 Q9LSD0
Caenorhabditis elegans (Cel) CE00874
(WBGene00004392)
GI:17551968 P42170
Caenorhabditis elegans (Cel) CE07085_2 GI:17567153 Q19599
Drosophila melanogaster (Dme) 7303545 GI:7303545
Homo sapiens (Hsa) Hs4557845
(RRM2)
GI:4557845 P31350
Homo sapiens (Hsa) Hs14743689 GI:14743689
Homo sapiens (Hsa) Hs17435183 GI:17435183
Saccharomyces cerevisiae (Sce) YGR180c
(S000003412)
GI:6321619 P49723
Saccharomyces cerevisiae (Sce) YJL026w
(S000003563)
GI:6322434 P09938
Schizosaccharomyces pombe (Spo) SPBC25D12.04 GI:19113338 P36603
Encephalitozoon cuniculi (Ecu) ECU06g0730 GI:19074323 Q8SRR2


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g27060
GO:0005634 nucleus C
IDA
SceS000003563
S000003412
SpoSPBC25D12.04
IGI
SpoSPBC25D12.04
GO:0005737 cytoplasm C
IDA
SceS000003412
S000003563
SpoSPBC25D12.04
NAS
HsaP31350
GO:0005829 cytosol C
IDA
SpoSPBC25D12.04
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003412
S000003563
IMP
SceS000003412
IPI
SceS000003412
TAS
SpoSPBC25D12.04
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IEP
SceS000003563
S000003412
IGI
SceS000003412
IPI
SceS000003412
ISS
SceS000003563
NAS
HsaP31350
RCA
AthAt3g27060
TAS
SpoSPBC25D12.04
GO:0005515 protein binding F
IPI
SpoSPBC25D12.04
GO:0000003 reproduction P
IMP
CelWBGene00004392
GO:0000074 regulation of progression through cell
cycle
P
IMP
AthAt3g27060
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPBC25D12.04
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00004392
GO:0006213 pyrimidine nucleoside metabolism P
IC
SpoSPBC25D12.04
GO:0006260 DNA replication P
IMP
AthAt3g27060
NAS
HsaP31350
TAS
SceS000003563
S000003412
SpoSPBC25D12.04
GO:0006281 DNA repair P
TAS
AthAt3g27060
GO:0007275 development P
IMP
AthAt3g27060
GO:0008340 determination of adult life span P
IMP
CelWBGene00004392
GO:0009186 deoxyribonucleoside diphosphate
metabolism
P
RCA
AthAt3g27060
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004392
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004392
GO:0042278 purine nucleoside metabolism P
IC
SpoSPBC25D12.04

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000003563

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000003563
(YJL026W)
Anopheles gambiae (Aga) 265 1 ENSANGP00000023621
Canis familiaris (Cfa) 259 1 ENSCAFP00000005080
Canis familiaris (Cfa) 259 0.355 ENSCAFP00000000854
Danio rerio (Dre) 176 1 ENSDARP00000008907
(rrm2)
P79733
Danio rerio (Dre) 176 0.199 ENSDARP00000050749
(rrm2b)
Q32PP6
Danio rerio (Dre) 176 0.071 ENSDARP00000011095
Takifugu rubripes (Fru) 261 1 SINFRUP00000153067
Takifugu rubripes (Fru) 261 0.201 SINFRUP00000140270
Gallus gallus (Gga) 231 1 ENSGALP00000026474
(RRM2)
Gallus gallus (Gga) 231 0.33 ENSGALP00000025808
(LOC420253)
Homo sapiens (Hsa) 272 1 ENSP00000302955
(RRM2)
P31350
Homo sapiens (Hsa) 272 0.322 ENSP00000251810
(RRM2B)
Q7LG56-1
Mus musculus (EMM) 249 1 ENSMUSP00000020980
(MGI:98181)
P11157
Mus musculus (EMM) 249 0.293 ENSMUSP00000022901
(MGI:2155865)
Q6PEE3
Pan troglodytes (Ptr) 206 1 ENSPTRP00000020027
Pan troglodytes (Ptr) 206 0.493 ENSPTRP00000035025
Rattus norvegicus (ERN) 240 1 ENSRNOP00000011163
(RGD:1559671)
Rattus norvegicus (ERN) 240 0.997 ENSRNOP00000037227
Rattus norvegicus (ERN) 240 0.107 ENSRNOP00000038047
(RGD:1306045)
Caenorhabditis elegans (Cel) 264 1 WBGene00004392
(CE00874)
P42170
Dictyostelium discoideum (Ddi) 316 1 DDB0185062
Dictyostelium discoideum (Ddi) 316 1 DDB0217423
Drosophila melanogaster (Dme) 271 1 CG8975-PA
(FBgn0011704)
Mus musculus (Mmu) 256 1 MGI:98181 P11157
Oryza sativa (Osa) 249 1 Q652F0 Q652F0
Oryza sativa (Osa) 249 0.858 Q8H638 Q8H638
Rattus norvegicus (Rno) 320 1 RGD:1306045
Schizosaccharomyces pombe (Spo) 462 1 SPBC25D12.04 P36603
Arabidopsis thaliana (Ath) 285 1 NP_189342
(At3g27060.1)
Q9LSD0
Arabidopsis thaliana (Ath) 285 0.262 NP_189000
(At3g23580.1)
P50651
Escherichia coli (Eco) 441 1 NP_416738
(EG10661)
P69924
Saccharomyces cerevisiae (Sce) 441 0.446 S000003412
(YGR180C)
Plasmodium falciparum (Pfa) 165 1 PF14_0053


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g27060
MmuMGI:2155865
PfaPF14_0053
GO:0005634 nucleus C
IDA
SceS000003563
S000003412
SpoSPBC25D12.04
IGI
SpoSPBC25D12.04
ISS
DdiDDB0185062
GO:0005737 cytoplasm C
IDA
SceS000003412
S000003563
SpoSPBC25D12.04
ISS
DdiDDB0185062
NAS
HsaP31350
GO:0005829 cytosol C
IDA
SpoSPBC25D12.04
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003412
S000003563
IMP
SceS000003412
IPI
SceS000003412
ISS
DdiDDB0185062
DmeFBgn0011704
NAS
DmeFBgn0011704
TAS
SpoSPBC25D12.04
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IDA
MmuMGI:2155865
IEP
SceS000003563
S000003412
IGI
SceS000003412
IPI
SceS000003412
ISS
DdiDDB0185062
DmeFBgn0011704
SceS000003563
NAS
HsaP31350
RCA
AthAt3g27060
TAS
SpoSPBC25D12.04
GO:0005515 protein binding F
IPI
EcoP69924
MmuMGI:98181
SpoSPBC25D12.04
GO:0000003 reproduction P
IMP
CelWBGene00004392
GO:0000074 regulation of progression through cell
cycle
P
IMP
AthAt3g27060
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPBC25D12.04
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00004392
GO:0006213 pyrimidine nucleoside metabolism P
IC
SpoSPBC25D12.04
GO:0006260 DNA replication P
IMP
AthAt3g27060
ISS
DdiDDB0185062
PfaPF14_0053
NAS
DmeFBgn0011704
HsaP31350
TAS
SceS000003563
S000003412
SpoSPBC25D12.04
GO:0006281 DNA repair P
TAS
AthAt3g27060
GO:0007275 development P
IMP
AthAt3g27060
GO:0008340 determination of adult life span P
IMP
CelWBGene00004392
GO:0009186 deoxyribonucleoside diphosphate
metabolism
P
ISS
DdiDDB0185062
RCA
AthAt3g27060
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009262 deoxyribonucleotide metabolism P
IDA
MmuMGI:98181
GO:0009263 deoxyribonucleotide biosynthesis P
IDA
MmuMGI:2155865
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004392
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004392
GO:0042278 purine nucleoside metabolism P
IC
SpoSPBC25D12.04

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
20277

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RRM2 GI:4557845 P31350
Canis familiaris (Cfa) LOC482963 GI:73979721
Mus musculus (Mmu) Rrm2
(MGI:98181)
GI:7106399 P11157
Rattus norvegicus (Rno) Rrm2_mapped
(RGD:3605)
GI:71043760 34381
Gallus gallus (Gga) RRM2 GI:50745023
Drosophila melanogaster (Dme) RnrS
(FBgn0011704)
GI:18079279 P48592
Anopheles gambiae (Aga) ENSANGG00000010722 GI:31199961 Q7PF28
Caenorhabditis elegans (Cel) rnr-2
(CE00874;
WBGene00004392)
GI:17551968 P42170
Schizosaccharomyces pombe (Spo) suc22
(SPBC25D12.04)
GI:19113338 P36603
Saccharomyces cerevisiae (Sce) RNR2
(S000003563)
GI:6322434 P09938
Kluyveromyces lactis (Kla) KLLA0F15103g GI:50311465 Q6CJY2
Eremothecium gossypii (Ego) AAL136C GI:45184688
Magnaporthe grisea (Mgr) MG06408.4 GI:39977011
Neurospora crassa (Ncr) GeneID:2710470 GI:32416230
Arabidopsis thaliana (Ath) RNR2A GI:15229476 P50651


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000003563
SpoSPBC25D12.04
IGI
SpoSPBC25D12.04
GO:0005737 cytoplasm C
IDA
SceS000003563
SpoSPBC25D12.04
ISS
RnoRGD:3605
NAS
HsaP31350
GO:0005829 cytosol C
IDA
SpoSPBC25D12.04
GO:0005971 ribonucleoside-diphosphate reductase
complex
C
IDA
SceS000003563
ISS
DmeFBgn0011704
NAS
DmeFBgn0011704
TAS
SpoSPBC25D12.04
GO:0004748 ribonucleoside-diphosphate reductase
activity
F
IEP
SceS000003563
ISS
DmeFBgn0011704
RnoRGD:3605
SceS000003563
NAS
HsaP31350
TAS
SpoSPBC25D12.04
GO:0005515 protein binding F
IPI
MmuMGI:98181
SpoSPBC25D12.04
ISS
RnoRGD:3605
GO:0000003 reproduction P
IMP
CelWBGene00004392
GO:0000084 S phase of mitotic cell cycle P
IC
SpoSPBC25D12.04
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00004392
GO:0006213 pyrimidine nucleoside metabolism P
IC
SpoSPBC25D12.04
GO:0006260 DNA replication P
ISS
RnoRGD:3605
NAS
DmeFBgn0011704
HsaP31350
TAS
SceS000003563
SpoSPBC25D12.04
GO:0008340 determination of adult life span P
IMP
CelWBGene00004392
GO:0009212 pyrimidine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009216 purine deoxyribonucleoside triphosphate
biosynthesis
P
IC
SpoSPBC25D12.04
GO:0009262 deoxyribonucleotide metabolism P
IDA
MmuMGI:98181
ISS
RnoRGD:3605
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004392
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004392
GO:0042278 purine nucleoside metabolism P
IC
SpoSPBC25D12.04

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_490

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga2274 ENSANGP00000013211
Anopheles gambiae (Aga) aga2275 ENSANGP00000023621
Ashbya gossypii (Ago) ago51 AAL136C
Arabidopsis thaliana (Ath) ath14676 At3g23580.1
Arabidopsis thaliana (Ath) ath15057 At3g27060.1
Arabidopsis thaliana (Ath) ath25873 At5g40942.1
Caenorhabditis elegans (Cel) cel917 C03C10.3
(CE00874;
WBGene00004392)
P42170
Candida glabrata (Cgl) cgl810 CAGL0D03432g
Cryptococcus neoformans (Cne) cne3556 176.m02292
Cryptococcus neoformans (Cne) cne3657 176.m02392
Dictyostelium discoideum (Ddi) ddi12045 DDB0185062
Dictyostelium discoideum (Ddi) ddi3771 DDB0217423
Debaryomyces hansenii (Dha) dha5914 DEHA0G04895g
Drosophila melanogaster (Dme) dme4579 CG8975-PA
(FBgn0011704)
Danio rerio (Dre) dre12640 ENSDARP00000008907
(rrm2)
P79733
Danio rerio (Dre) dre10458 ENSDARP00000011095
Danio rerio (Dre) dre12639 ENSDARP00000029258
Danio rerio (Dre) dre10466 ENSDARP00000050749
(rrm2b)
Q32PP6
Escherichia coli (Eco) eco2164 16130170
(EG10661)
P69924
Encephalitozoon cuniculi (Ecu) ecu1550 19074323
Takifugu rubripes (Fru) fru20147 SINFRUP00000140270
Takifugu rubripes (Fru) fru18375 SINFRUP00000153067
Gallus gallus (Gga) gga11400 ENSGALP00000025808
(LOC420253)
Gallus gallus (Gga) gga15966 ENSGALP00000026474
(RRM2)
Homo sapiens (Hsa) hsa30597 ENSP00000251810
(RRM2B)
Q7LG56-1
Homo sapiens (Hsa) hsa17459 ENSP00000302955
(RRM2)
P31350
Kluyveromyces lactis (Kla) kla4757 KLLA0F15103g
Mus musculus (Mmu) mmu5552 ENSMUSP00000020980
(MGI:98181)
P11157
Mus musculus (Mmu) mmu8906 ENSMUSP00000022901
(MGI:2155865)
Q6PEE3
Neurospora crassa (Ncr) ncr7683 NCU07887.2
Oryza sativa (Osa) osa44698 5621.m00201
Oryza sativa (Osa) osa50018 5749.m00174
Oryza sativa (Osa) osa67018 6942.m00101
Plasmodium falciparum (Pfa) pfa375 PF10_0154
Plasmodium falciparum (Pfa) pfa1309 PF14_0053
Rattus norvegicus (Rno) rno14764 ENSRNOP00000011163
(RGD:1559671)
Rattus norvegicus (Rno) rno24937 ENSRNOP00000037227
Rattus norvegicus (Rno) rno26980 ENSRNOP00000038047
(RGD:1306045)
Saccharomyces cerevisiae (Sce) sce3282 YJL026W
(S000003563)
Schizosaccharomyces pombe (Spo) spo1823 SPBC25D12.04 P36603
Yarrowia lipolytica (Yli) yli894 YALI0B03630g