YOGY Home YOGY Help

Search term: YHR007C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG11
SGD link S000001049
Alternative ID YHR007C
Description Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family
Synonyms YHR007C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0684 A--HYP-

KOGs classification KOGs description
Q
METABOLISM
Secondary metabolites biosynthesis, transport and catabolism
Cytochrome P450

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g11680 GI:15221075 Q9SAA9
Arabidopsis thaliana (Ath) At2g17330 GI:15227817
Homo sapiens (Hsa) Hs13650621 GI:13650621
Homo sapiens (Hsa) Hs13699859
(PTGIS)
GI:13699859 Q16647
Homo sapiens (Hsa) Hs13929429
(CYP8B1)
GI:13929429 Q9UNU6
Homo sapiens (Hsa) Hs4503243
(CYP51A1)
GI:4503243 Q16850
Homo sapiens (Hsa) Hs4503245
(CYP7A1)
GI:4503245 P22680
Homo sapiens (Hsa) Hs4758104
(CYP7B1)
GI:4758104 O75881
Homo sapiens (Hsa) Hs7706129 GI:7706129
Saccharomyces cerevisiae (Sce) YHR007c
(S000001049)
GI:6321795 P10614
Schizosaccharomyces pombe (Spo) SPAC13A11.02c GI:19113902 Q09736


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000001049
SpoSPAC13A11.02c
TAS
SceS000001049
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC13A11.02c
GO:0008116 prostaglandin-I synthase activity F
TAS
HsaQ16647
GO:0008396 oxysterol 7-alpha-hydroxylase activity F
TAS
HsaO75881
GO:0008397 sterol 12-alpha-hydroxylase activity F
TAS
HsaQ9UNU6
GO:0008398 sterol 14-demethylase activity F
ISS
SpoSPAC13A11.02c
TAS
SceS000001049
GO:0019825 oxygen binding F
RCA
AthAt2g17330
TAS
HsaQ9UNU6
GO:0006629 lipid metabolism P
NAS
HsaQ16647
GO:0006696 ergosterol biosynthesis P
ISS
SpoSPAC13A11.02c
TAS
SceS000001049
GO:0006699 bile acid biosynthesis P
NR
HsaP22680
TAS
HsaO75881
GO:0016126 sterol biosynthesis P
TAS
AthAt1g11680

Back to the top

Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000001049

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000001049
(YHR007C)
Anopheles gambiae (Aga) 1527 1 ENSANGP00000022378
Anopheles gambiae (Aga) 1527 0.383 ENSANGP00000014254
Anopheles gambiae (Aga) 1527 0.368 ENSANGP00000019301
Anopheles gambiae (Aga) 1527 0.342 ENSANGP00000010558
Anopheles gambiae (Aga) 1527 0.335 ENSANGP00000020095
Anopheles gambiae (Aga) 1527 0.328 ENSANGP00000010494
Anopheles gambiae (Aga) 1527 0.316 ENSANGP00000010492
Anopheles gambiae (Aga) 1527 0.311 ENSANGP00000023901
Anopheles gambiae (Aga) 1527 0.299 ENSANGP00000020821
Anopheles gambiae (Aga) 1527 0.294 ENSANGP00000024957
Anopheles gambiae (Aga) 1527 0.292 ENSANGP00000019380
Anopheles gambiae (Aga) 1527 0.291 ENSANGP00000002214
Anopheles gambiae (Aga) 1527 0.286 ENSANGP00000019496
Anopheles gambiae (Aga) 1527 0.284 ENSANGP00000001916
Anopheles gambiae (Aga) 1527 0.279 ENSANGP00000008167
Anopheles gambiae (Aga) 1527 0.266 ENSANGP00000024886
Anopheles gambiae (Aga) 1527 0.263 ENSANGP00000012521
Anopheles gambiae (Aga) 1527 0.262 ENSANGP00000010286
Anopheles gambiae (Aga) 1527 0.247 ENSANGP00000016970
Anopheles gambiae (Aga) 1527 0.247 ENSANGP00000014843
Anopheles gambiae (Aga) 1527 0.236 ENSANGP00000019843
Anopheles gambiae (Aga) 1527 0.202 ENSANGP00000019660
Anopheles gambiae (Aga) 1527 0.198 ENSANGP00000011391
Anopheles gambiae (Aga) 1527 0.17 ENSANGP00000013504
Anopheles gambiae (Aga) 1527 0.144 ENSANGP00000006290
Anopheles gambiae (Aga) 1527 0.138 ENSANGP00000025098
Anopheles gambiae (Aga) 1527 0.131 ENSANGP00000006206
Anopheles gambiae (Aga) 1527 0.123 ENSANGP00000013571
Anopheles gambiae (Aga) 1527 0.122 ENSANGP00000012179
Anopheles gambiae (Aga) 1527 0.11 ENSANGP00000019398
Anopheles gambiae (Aga) 1527 0.106 ENSANGP00000013480
Anopheles gambiae (Aga) 1527 0.08 ENSANGP00000009680
Anopheles gambiae (Aga) 1527 0.069 ENSANGP00000026599
Anopheles gambiae (Aga) 1527 0.068 ENSANGP00000024695
Anopheles gambiae (Aga) 1527 0.066 ENSANGP00000019705
Anopheles gambiae (Aga) 1527 0.064 ENSANGP00000004678
Saccharomyces cerevisiae (Sce) 1208 1 S000004617
(YMR015C)
Canis familiaris (Cfa) 527 1 ENSCAFP00000002855
Danio rerio (Dre) 1299 1 ENSDARP00000016128
(si:dkey-69h9.1)
Q5VSI8
Danio rerio (Dre) 1299 0.796 ENSDARP00000049442
Takifugu rubripes (Fru) 578 1 SINFRUP00000135614
Gallus gallus (Gga) 459 1 ENSGALP00000015237
(CYP51)
Q0KKP5
Homo sapiens (Hsa) 519 1 ENSP00000003100
(CYP51A1)
Q16850
Mus musculus (EMM) 502 1 ENSMUSP00000001507
(MGI:106040)
Q8BSQ7
Pan troglodytes (Ptr) 430 1 ENSPTRP00000033177
Rattus norvegicus (ERN) 489 1 ENSRNOP00000009985
(RGD:2481)
Q64654
Caenorhabditis elegans (Cel) 1445 1 WBGene00011830
(CE06455)
Caenorhabditis elegans (Cel) 1445 0.571 WBGene00007140
(CE15551)
Caenorhabditis elegans (Cel) 1445 0.546 WBGene00021412
(CE35365)
Caenorhabditis elegans (Cel) 1445 0.366 WBGene00008083
Caenorhabditis elegans (Cel) 1445 0.262 WBGene00008499
(CE35449)
Caenorhabditis elegans (Cel) 1445 0.252 WBGene00009226
(CE15919)
Caenorhabditis elegans (Cel) 1445 0.211 WBGene00021167
(CE26222)
Caenorhabditis elegans (Cel) 1445 0.209 WBGene00021200
(CE24183)
Caenorhabditis elegans (Cel) 1445 0.205 WBGene00010354
(CE37719)
Caenorhabditis elegans (Cel) 1445 0.184 WBGene00013585
(CE36516)
Caenorhabditis elegans (Cel) 1445 0.184 WBGene00016147
(CE39228)
Dictyostelium discoideum (Ddi) 1627 1 DDB0218166
Drosophila melanogaster (Dme) 1502 1 CG10246-PA
(FBgn0013771)
Drosophila melanogaster (Dme) 1502 0.838 CG10247-PA
(FBgn0033981)
Drosophila melanogaster (Dme) 1502 0.517 CG9438-PA
(FBgn0000473)
Drosophila melanogaster (Dme) 1502 0.499 CG10248-PA
(FBgn0013772)
Drosophila melanogaster (Dme) 1502 0.48 CG13977-PA
(FBgn0039519)
Drosophila melanogaster (Dme) 1502 0.422 CG10241-PA
(FBgn0015714)
Drosophila melanogaster (Dme) 1502 0.409 CG10242-PA
(FBgn0033978)
Drosophila melanogaster (Dme) 1502 0.406 CG10240-PA
(FBgn0013773)
Drosophila melanogaster (Dme) 1502 0.391 CG10245-PA
(FBgn0033980)
Drosophila melanogaster (Dme) 1502 0.369 CG2397-PA
(FBgn0033304)
Drosophila melanogaster (Dme) 1502 0.369 CG10243-PA
(FBgn0033979)
Drosophila melanogaster (Dme) 1502 0.354 CG8687-PB
(FBgn0033302)
Drosophila melanogaster (Dme) 1502 0.231 CG17453-PA
(FBgn0033982)
Drosophila melanogaster (Dme) 1502 0.216 CG8453-PA
(FBgn0025454)
Drosophila melanogaster (Dme) 1502 0.214 CG8859-PA
(FBgn0033696)
Drosophila melanogaster (Dme) 1502 0.202 CG12800-PA
(FBgn0039006)
Drosophila melanogaster (Dme) 1502 0.197 CG3050-PA
(FBgn0038194)
Drosophila melanogaster (Dme) 1502 0.192 CG8345-PA
(FBgn0033065)
Drosophila melanogaster (Dme) 1502 0.19 CG4373-PA
(FBgn0034756)
Drosophila melanogaster (Dme) 1502 0.174 CG3567-PA
(FBgn0033121)
Drosophila melanogaster (Dme) 1502 0.174 CG11466-PA
(FBgn0038037)
Drosophila melanogaster (Dme) 1502 0.167 CG1829-PA
(FBgn0031126)
Drosophila melanogaster (Dme) 1502 0.148 CG1644-PA
(FBgn0031182)
Drosophila melanogaster (Dme) 1502 0.14 CG4485-PA
(FBgn0015038)
Drosophila melanogaster (Dme) 1502 0.134 CG4486-PA
(FBgn0015039)
Drosophila melanogaster (Dme) 1502 0.118 CG8457-PA
(FBgn0033697)
Drosophila melanogaster (Dme) 1502 0.109 CG17577-PA
(FBgn0033775)
Drosophila melanogaster (Dme) 1502 0.104 CG8864-PA
(FBgn0028940)
Drosophila melanogaster (Dme) 1502 0.096 CG9964-PA
(FBgn0031432)
Drosophila melanogaster (Dme) 1502 0.092 CG3616-PA
(FBgn0015040)
Drosophila melanogaster (Dme) 1502 0.082 CG6081-PA
(FBgn0031688)
Drosophila melanogaster (Dme) 1502 0.079 CG1895-PA
(FBgn0030339)
Drosophila melanogaster (Dme) 1502 0.067 CG10833-PA
(FBgn0031689)
Drosophila melanogaster (Dme) 1502 0.055 CG6585-PA
(FBgn0030949)
Mus musculus (Mmu) 503 1 MGI:106040 Q8BSQ7
Oryza sativa (Osa) 681 1 Q9SXU9 Q9SXU9
Oryza sativa (Osa) 681 0.452 Q6L4I8 Q6L4I8
Oryza sativa (Osa) 681 0.414 Q6AT75 Q6AT75
Oryza sativa (Osa) 681 0.369 Q8GTY5 Q8GTY5
Oryza sativa (Osa) 681 0.364 Q6ZH24 Q6ZH24
Oryza sativa (Osa) 681 0.36 Q84LF7 Q84LF7
Oryza sativa (Osa) 681 0.338 Q6AT81 Q6AT81
Oryza sativa (Osa) 681 0.33 Q6Z6U3 Q6Z6U3
Oryza sativa (Osa) 681 0.244 Q6AT80 Q6AT80
Rattus norvegicus (Rno) 437 1 RGD:2481 41312
Schizosaccharomyces pombe (Spo) 469 1 SPAC13A11.02c Q09736
Arabidopsis thaliana (Ath) 718 1 NP_172633
(At1g11680.1)
Q9SAA9


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005615 extracellular space C
ISS
RnoRGD:2481
RCA
MmuMGI:106040
GO:0005783 endoplasmic reticulum C
IDA
SceS000001049
SpoSPAC13A11.02c
TAS
SceS000004617
S000001049
GO:0005789 endoplasmic reticulum membrane C
ISS
SpoSPAC13A11.02c
GO:0005792 microsome C
NAS
DmeFBgn0033981
FBgn0013771
FBgn0000473
FBgn0013772
FBgn0015714
FBgn0039519
FBgn0033978
FBgn0013773
FBgn0033980
FBgn0033304
FBgn0033979
FBgn0033302
FBgn0033982
FBgn0025454
FBgn0033696
FBgn0039006
FBgn0038194
FBgn0033065
FBgn0034756
FBgn0033121
FBgn0038037
FBgn0031126
FBgn0031182
FBgn0015038
FBgn0015039
FBgn0033697
FBgn0033775
FBgn0028940
FBgn0031432
FBgn0015040
FBgn0031688
FBgn0030339
FBgn0031689
FBgn0030949
GO:0016020 membrane C
NAS
DmeFBgn0033981
FBgn0013772
FBgn0013771
FBgn0039519
FBgn0015714
FBgn0033978
FBgn0013773
FBgn0033980
FBgn0033304
FBgn0033979
FBgn0033302
FBgn0033982
FBgn0000473
FBgn0025454
FBgn0039006
FBgn0033696
FBgn0038194
FBgn0033065
FBgn0034756
FBgn0033121
FBgn0038037
FBgn0031126
FBgn0031182
FBgn0015038
FBgn0015039
FBgn0033697
FBgn0033775
FBgn0028940
FBgn0031432
FBgn0015040
FBgn0031688
FBgn0030339
FBgn0031689
FBgn0030949
GO:0016021 integral to membrane C
ISS
RnoRGD:2481
RCA
MmuMGI:106040
GO:0000249 C-22 sterol desaturase activity F
TAS
SceS000004617
GO:0004295 trypsin activity F
ISS
RnoRGD:2481
RCA
MmuMGI:106040
GO:0008393 fatty acid (omega-1)-hydroxylase
activity
F
IDA
DmeFBgn0013772
GO:0008398 sterol 14-demethylase activity F
IDA
RnoRGD:2481
ISS
RnoRGD:2481
SpoSPAC13A11.02c
TAS
MmuMGI:106040
SceS000001049
GO:0009055 electron carrier activity F
ISS
DmeFBgn0000473
FBgn0033981
FBgn0013772
FBgn0039519
FBgn0033978
FBgn0015714
FBgn0013773
FBgn0033980
FBgn0033304
FBgn0033979
FBgn0033302
FBgn0033982
FBgn0025454
FBgn0013771
FBgn0033696
FBgn0038194
FBgn0039006
FBgn0033065
FBgn0034756
FBgn0033121
FBgn0038037
FBgn0031126
FBgn0031182
FBgn0015038
FBgn0015039
FBgn0033697
FBgn0033775
FBgn0028940
FBgn0031432
FBgn0015040
FBgn0031688
FBgn0030339
FBgn0031689
FBgn0030949
NAS
DmeFBgn0000473
FBgn0013771
FBgn0013772
FBgn0039519
FBgn0015714
FBgn0033978
FBgn0013773
FBgn0033980
FBgn0033304
FBgn0033979
FBgn0033302
FBgn0033981
FBgn0033982
FBgn0025454
FBgn0039006
FBgn0033696
FBgn0038194
FBgn0033065
FBgn0034756
FBgn0033121
FBgn0038037
FBgn0031126
FBgn0031182
FBgn0015038
FBgn0015039
FBgn0033697
FBgn0033775
FBgn0028940
FBgn0031432
FBgn0015040
FBgn0031688
FBgn0030339
FBgn0031689
FBgn0030949
GO:0020037 heme binding F
ISS
RnoRGD:2481
GO:0000910 cytokinesis P
IMP
CelWBGene00010354
WBGene00021200
GO:0006118 electron transport P
ISS
RnoRGD:2481
RCA
MmuMGI:106040
GO:0006508 proteolysis P
ISS
RnoRGD:2481
RCA
MmuMGI:106040
GO:0006695 cholesterol biosynthesis P
ISS
RnoRGD:2481
TAS
MmuMGI:106040
GO:0006696 ergosterol biosynthesis P
ISS
SpoSPAC13A11.02c
TAS
SceS000001049
S000004617
GO:0007308 oocyte construction P
IMP
CelWBGene00010354
WBGene00021200
GO:0007626 locomotory behavior P
IMP
CelWBGene00013585
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00010354
WBGene00021200
WBGene00013585
GO:0016126 sterol biosynthesis P
TAS
AthAt1g11680
GO:0017085 response to insecticide P
IDA
DmeFBgn0000473
IMP
DmeFBgn0025454
GO:0017143 insecticide metabolism P
IDA
DmeFBgn0013772
NAS
DmeFBgn0013771
FBgn0030949
GO:0045540 regulation of cholesterol biosynthesis P
TAS
RnoRGD:2481
GO:0046680 response to DDT P
IMP
DmeFBgn0025454
GO:0046683 response to organophosphorus P
IMP
DmeFBgn0025454
GO:0048252 lauric acid metabolism P
IDA
DmeFBgn0013772

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55488

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) CYP51A1 GI:4503243 Q16850
Pan troglodytes (Ptr) CYP51A1 GI:114614422
Canis familiaris (Cfa) LOC475225 GI:57095976
Mus musculus (Mmu) Cyp51
(MGI:106040)
GI:71061451 Q8BSQ7
Rattus norvegicus (Rno) Cyp51
(RGD:2481)
GI:6978751 41312
Gallus gallus (Gga) CYP51 GI:50732469
Schizosaccharomyces pombe (Spo) cyp51
(SPAC13A11.02c)
GI:19113902 Q09736
Saccharomyces cerevisiae (Sce) ERG11
(S000001049)
GI:6321795 P10614
Kluyveromyces lactis (Kla) KLLA0E03553g GI:50308217 Q6CPN0
Eremothecium gossypii (Ego) ADR162W GI:45188036
Magnaporthe grisea (Mgr) MG04628.4 GI:39945292
Arabidopsis thaliana (Ath) CYP51G1 GI:15221075 Q9SAA9
Oryza sativa (Osa) OSJNBa0074P11.4 GI:50933233