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Search term: YGR188C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name BUB1
SGD link S000003420
Alternative ID YGR188C
Description Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p
Synonyms YGR188C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1166 ACDHYP-

KOGs classification KOGs description
D
CELLULAR PROCESSES AND SIGNALING
Cell cycle control, cell division, chromosome partitioning
Mitotic checkpoint serine/threonine protein kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g20635 GI:15225393 Q8S8D9
Arabidopsis thaliana (Ath) At2g33560 GI:15226131
Arabidopsis thaliana (Ath) At5g05510 GI:15239147 Q9FFG4
Caenorhabditis elegans (Cel) CE06251_2 GI:17508581 Q21776
Caenorhabditis elegans (Cel) CE15187 GI:17510989
Drosophila melanogaster (Dme) 7296964
(FBgn0031696)
GI:19920746 Q9VMS5
Drosophila melanogaster (Dme) 7302202
(FBgn0025458)
GI:17137586
Homo sapiens (Hsa) Hs20149509 GI:20149509
Homo sapiens (Hsa) Hs4757878
(BUB1)
GI:4757878 O43683
Saccharomyces cerevisiae (Sce) YGR188c
(S000003420)
GI:6321627 P41695
Saccharomyces cerevisiae (Sce) YJL013c
(S000003550)
GI:6322447 P47074
Schizosaccharomyces pombe (Spo) SPCC1322.12c GI:19075640 O94751


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
DmeFBgn0025458
SceS000003420
TAS
DmeFBgn0025458
HsaO43683
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000003420
SpoSPCC1322.12c
GO:0000780 condensed nuclear chromosome, pericentric
region
C
IDA
SceS000003420
GO:0000940 outer kinetochore of condensed
chromosome
C
NAS
DmeFBgn0025458
GO:0005575 cellular_component C
ND
AthAt5g05510
At2g20635
GO:0005634 nucleus C
IDA
SceS000003550
S000003420
SpoSPCC1322.12c
GO:0005737 cytoplasm C
IDA
DmeFBgn0025458
GO:0005816 spindle pole body C
TAS
HsaO43683
GO:0003674 molecular_function F
ND
AthAt5g05510
At2g20635
SceS000003550
GO:0004672 protein kinase activity F
IDA
SceS000003420
NAS
DmeFBgn0031696
FBgn0025458
GO:0004674 protein serine/threonine kinase
activity
F
ISS
DmeFBgn0025458
FBgn0031696
NAS
DmeFBgn0025458
TAS
SpoSPCC1322.12c
GO:0005515 protein binding F
IPI
SceS000003420
SpoSPCC1322.12c
GO:0000003 reproduction P
IMP
CelWBGene00000275
GO:0000910 cytokinesis P
IMP
CelWBGene00000275
GO:0002009 morphogenesis of an epithelium P
IMP
CelWBGene00000275
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000003420
NAS
DmeFBgn0025458
FBgn0031696
GO:0007094 mitotic spindle checkpoint P
IDA
DmeFBgn0025458
FBgn0031696
IGI
SceS000003550
IMP
DmeFBgn0025458
SceS000003550
SpoSPCC1322.12c
ISS
DmeFBgn0025458
TAS
DmeFBgn0025458
HsaO43683
SceS000003420
GO:0007096 regulation of exit from mitosis P
IGI
DmeFBgn0025458
IMP
DmeFBgn0025458
GO:0007276 gametogenesis P
IMP
CelWBGene00000275
GO:0007582 physiological process P
IMP
CelWBGene00000275
GO:0007626 locomotory behavior P
IMP
CelWBGene00000275
GO:0008104 protein localization P
IGI
SpoSPCC1322.12c
GO:0008150 biological_process P
ND
AthAt2g20635
At5g05510
GO:0008283 cell proliferation P
TAS
HsaO43683
GO:0008608 attachment of spindle microtubules to
kinetochore
P
IGI
SpoSPCC1322.12c
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00000275
GO:0031577 spindle checkpoint P
IMP
DmeFBgn0025458
GO:0035186 syncytial blastoderm mitotic cell
cycle
P
IMP
DmeFBgn0025458
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00000275
GO:0051177 meiotic sister chromatid cohesion P
IGI
SpoSPCC1322.12c

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000003420

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000003420
(YGR188C)
Anopheles gambiae (Aga) 876 1 ENSANGP00000008371
Saccharomyces cerevisiae (Sce) 1378 1 S000003550
(YJL013C)
Saccharomyces cerevisiae (Sce) 1812 1 S000003550
(YJL013C)
Canis familiaris (Cfa) 1347 1 ENSCAFP00000013122
Danio rerio (Dre) 1433 1 ENSDARP00000025686
Saccharomyces cerevisiae (Sce) 1433 1 S000003550
(YJL013C)
Saccharomyces cerevisiae (Sce) 1696 1 S000003550
(YJL013C)
Takifugu rubripes (Fru) 1696 1 SINFRUP00000165671
Gallus gallus (Gga) 1455 1 ENSGALP00000007713
(RCJMB04_19f17)
Q5F3E7
Saccharomyces cerevisiae (Sce) 1455 1 S000003550
(YJL013C)
Homo sapiens (Hsa) 1343 1 ENSP00000287598
(BUB1B)
O60566
Homo sapiens (Hsa) 1343 0.071 ENSP00000302530
(BUB1)
Mus musculus (EMM) 1365 1 ENSMUSP00000037126
(MGI:1333889)
Q9Z1S0
Mus musculus (EMM) 1365 0.065 ENSMUSP00000028858
(MGI:1100510)
Pan troglodytes (Ptr) 980 1 ENSPTRP00000021142
Rattus norvegicus (ERN) 869 1 ENSRNOP00000021619
Saccharomyces cerevisiae (Sce) 1540 1 S000003550
(YJL013C)
Saccharomyces cerevisiae (Sce) 1781 1 S000003550
(YJL013C)
Saccharomyces cerevisiae (Sce) 1813 1 S000003550
(YJL013C)
Caenorhabditis elegans (Cel) 1813 1 WBGene00004721
(CE34445)
Dictyostelium discoideum (Ddi) 1047 1 DDB0184518
Drosophila melanogaster (Dme) 826 1 CG14030-PA
(FBgn0031696)
Drosophila melanogaster (Dme) 826 0.085 CG7838-PA
(FBgn0025458)
Mus musculus (Mmu) 882 1 MGI:1100510 O08901
Oryza sativa (Osa) 919 1 Q7XIR5 Q7XIR5
Rattus norvegicus (Rno) 746 1 RGD:1311707
Schizosaccharomyces pombe (Spo) 1077 1 SPCC1322.12c O94751
Arabidopsis thaliana (Ath) 1591 1 NP_565767
(At2g33560.1)
O22806
Saccharomyces cerevisiae (Sce) 1591 1 S000003550
(YJL013C)


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000775 chromosome, pericentric region C
IDA
MmuMGI:1100510
ISS
RnoRGD:1311707
GO:0000776 kinetochore C
IDA
DmeFBgn0025458
MmuMGI:1333889
MGI:1100510
SceS000003420
ISS
RnoRGD:1311707
NAS
HsaO60566
TAS
DmeFBgn0025458
HsaO60566
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000003420
SpoSPCC1322.12c
GO:0000780 condensed nuclear chromosome, pericentric
region
C
IDA
SceS000003420
GO:0000940 outer kinetochore of condensed
chromosome
C
IDA
MmuMGI:1333889
NAS
DmeFBgn0025458
GO:0005634 nucleus C
IDA
SceS000003550
S000003420
SpoSPCC1322.12c
GO:0005680 anaphase-promoting complex C
TAS
HsaO60566
GO:0005737 cytoplasm C
IDA
DmeFBgn0025458
HsaO60566
GO:0005816 spindle pole body C
ISS
RnoRGD:1311707
GO:0051233 spindle midzone C
NAS
HsaO60566
GO:0003674 molecular_function F
ND
SceS000003550
GO:0004672 protein kinase activity F
IDA
SceS000003420
NAS
DmeFBgn0031696
FBgn0025458
GO:0004674 protein serine/threonine kinase
activity
F
ISS
DmeFBgn0025458
FBgn0031696
NAS
DmeFBgn0025458
TAS
SpoSPCC1322.12c
GO:0005515 protein binding F
IPI
HsaO60566
SceS000003420
SpoSPCC1322.12c
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000003420
NAS
DmeFBgn0025458
FBgn0031696
GO:0007049 cell cycle P
NAS
HsaO60566
GO:0007051 spindle organization and biogenesis P
NAS
HsaO60566
GO:0007067 mitosis P
NAS
HsaO60566
GO:0007093 mitotic checkpoint P
TAS
HsaO60566
GO:0007094 mitotic spindle checkpoint P
IDA
DmeFBgn0025458
FBgn0031696
IGI
SceS000003550
IMP
DmeFBgn0025458
SceS000003550
SpoSPCC1322.12c
ISS
DmeFBgn0025458
RnoRGD:1311707
TAS
DmeFBgn0025458
SceS000003420
GO:0007096 regulation of exit from mitosis P
IGI
DmeFBgn0025458
IMP
DmeFBgn0025458
GO:0008104 protein localization P
IGI
SpoSPCC1322.12c
GO:0008283 cell proliferation P
ISS
RnoRGD:1311707
TAS
HsaO60566
GO:0008608 attachment of spindle microtubules to
kinetochore
P
IGI
SpoSPCC1322.12c
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004721
GO:0031577 spindle checkpoint P
IMP
DmeFBgn0025458
GO:0035186 syncytial blastoderm mitotic cell
cycle
P
IMP
DmeFBgn0025458
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaO60566
GO:0051177 meiotic sister chromatid cohesion P
IGI
SpoSPCC1322.12c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39155

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) bub1
(SPCC1322.12c)
GI:19075640 O94751
Saccharomyces cerevisiae (Sce) BUB1
(S000003420)
GI:6321627 P41695
Kluyveromyces lactis (Kla) KLLA0F22605g GI:50312117 Q6CIZ9
Eremothecium gossypii (Ego) AGR315C GI:45201411
Magnaporthe grisea (Mgr) MG10608.4 GI:39969999
Neurospora crassa (Ncr) GeneID:2705054 GI:32405098
Oryza sativa (Osa) OJ1163_G04.108 GI:50937595


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000776 kinetochore C
IDA
SceS000003420
GO:0000778 condensed nuclear chromosome kinetochore C
IDA
SceS000003420
SpoSPCC1322.12c
GO:0000780 condensed nuclear chromosome, pericentric
region
C
IDA
SceS000003420
GO:0005634 nucleus C
IDA
SceS000003420
SpoSPCC1322.12c
GO:0004672 protein kinase activity F
IDA
SceS000003420
GO:0004674 protein serine/threonine kinase
activity
F
TAS
SpoSPCC1322.12c
GO:0005515 protein binding F
IPI
SceS000003420
SpoSPCC1322.12c
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000003420
GO:0007094 mitotic spindle checkpoint P
IMP
SpoSPCC1322.12c
TAS
SceS000003420
GO:0008104 protein localization P
IGI
SpoSPCC1322.12c
GO:0008608 attachment of spindle microtubules to
kinetochore
P
IGI
SpoSPCC1322.12c
GO:0051177 meiotic sister chromatid cohesion P
IGI
SpoSPCC1322.12c

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