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Search term: YDR217C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RAD9
SGD link S000002625
Alternative ID YDR217C
Description DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate
Synonyms YDR217C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3548 -C-HYP-

KOGs classification KOGs description
L
INFORMATION STORAGE AND PROCESSING
Replication, recombination and repair
DNA damage checkpoint protein RHP9/CRB2/53BP1

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE20034 GI:17508885
Caenorhabditis elegans (Cel) CE20035 GI:17508887
Homo sapiens (Hsa) Hs5032189
(TP53BP1)
GI:5032189 Q12888
Saccharomyces cerevisiae (Sce) YDR217c
(S000002625)
GI:6320423 P14737
Schizosaccharomyces pombe (Spo) SPBC342.05 GI:19113540 P87074


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
ISS
SpoSPBC342.05
GO:0005634 nucleus C
IC
SceS000002625
IDA
SpoSPBC342.05
GO:0005654 nucleoplasm C
IDA
HsaQ12888
GO:0005737 cytoplasm C
IDA
HsaQ12888
GO:0005515 protein binding F
IDA
SceS000002625
IPI
HsaQ12888
SpoSPBC342.05
GO:0016563 transcriptional activator activity F
NAS
HsaQ12888
GO:0042802 identical protein binding F
IPI
SpoSPBC342.05
GO:0000074 regulation of progression through cell
cycle
P
IGI
SceS000002625
IMP
SceS000002625
GO:0000077 DNA damage checkpoint P
IMP
SceS000002625
SpoSPBC342.05
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SpoSPBC342.05
GO:0006281 DNA repair P
IGI
SceS000002625
IMP
SceS000002625
GO:0006289 nucleotide-excision repair P
IMP
SceS000002625
GO:0045893 positive regulation of transcription,
DNA-dependent
P
NAS
HsaQ12888
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002625

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
48635

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) RAD9
(S000002625)
GI:6320423 P14737
Kluyveromyces lactis (Kla) KLLA0F13068g GI:50311287 Q6CK71


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IC
SceS000002625
GO:0005515 protein binding F
IDA
SceS000002625
GO:0000074 regulation of progression through cell
cycle
P
IGI
SceS000002625
IMP
SceS000002625
GO:0000077 DNA damage checkpoint P
IMP
SceS000002625
GO:0006281 DNA repair P
IGI
SceS000002625
IMP
SceS000002625
GO:0006289 nucleotide-excision repair P
IMP
SceS000002625
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002625

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_13163

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Ashbya gossypii (Ago) ago4484 AGR173C
Candida glabrata (Cgl) cgl1152 CAGL0E04862g
Cryptococcus neoformans (Cne) cne517 163.m06516
Debaryomyces hansenii (Dha) dha4075 DEHA0E18821g
Kluyveromyces lactis (Kla) kla4668 KLLA0F13068g
Neurospora crassa (Ncr) ncr8653 NCU08879.2
Saccharomyces cerevisiae (Sce) sce1265 YDR217C
(S000002625)
Schizosaccharomyces pombe (Spo) spo3989 SPBC342.05 P87074
Yarrowia lipolytica (Yli) yli5155 YALI0E31273g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
ISS
SpoSPBC342.05
GO:0005634 nucleus C
IC
SceS000002625
IDA
SpoSPBC342.05
GO:0005515 protein binding F
IDA
SceS000002625
IPI
SpoSPBC342.05
GO:0042802 identical protein binding F
IPI
SpoSPBC342.05
GO:0000074 regulation of progression through cell
cycle
P
IGI
SceS000002625
IMP
SceS000002625
GO:0000077 DNA damage checkpoint P
IMP
SceS000002625
SpoSPBC342.05
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SpoSPBC342.05
GO:0006281 DNA repair P
IGI
SceS000002625
IMP
SceS000002625
GO:0006289 nucleotide-excision repair P
IMP
SceS000002625
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002625

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC342.05
(P87074)
YDR217C
(S000002625)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
ISS
SpoSPBC342.05
GO:0005634 nucleus C
IC
SceS000002625
IDA
SpoSPBC342.05
GO:0005515 protein binding F
IDA
SceS000002625
IPI
SpoSPBC342.05
GO:0042802 identical protein binding F
IPI
SpoSPBC342.05
GO:0000074 regulation of progression through cell
cycle
P
IGI
SceS000002625
IMP
SceS000002625
GO:0000077 DNA damage checkpoint P
IMP
SceS000002625
SpoSPBC342.05
GO:0000082 G1/S transition of mitotic cell
cycle
P
IPI
SpoSPBC342.05
GO:0006281 DNA repair P
IGI
SceS000002625
IMP
SceS000002625
GO:0006289 nucleotide-excision repair P
IMP
SceS000002625
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter
P
IMP
SceS000002625

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GO info in one table:

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