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Search term: YDL003W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MCD1
SGD link S000002161
Alternative ID YDL003W
Description Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase
Synonyms YDL003W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1213 ACDHYPE

KOGs classification KOGs description
D
CELLULAR PROCESSES AND SIGNALING
Cell cycle control, cell division, chromosome partitioning
Sister chromatid cohesion complex Cohesin, subunit RAD21/SCC1

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g59550 GI:15231707 Q9FQ19
Arabidopsis thaliana (Ath) At5g05490 GI:15239141 Q9S7T7
Arabidopsis thaliana (Ath) At5g16270 GI:15237318
Arabidopsis thaliana (Ath) At5g40840 GI:10177963
Caenorhabditis elegans (Cel) CE02628
(WBGene00004737)
GI:17532617 Q19325
Caenorhabditis elegans (Cel) CE04726
(WBGene00000591)
GI:17551254 Q21306
Drosophila melanogaster (Dme) 7289833 GI:7289833
Homo sapiens (Hsa) Hs5453994
(RAD21)
GI:5453994 O60216
Homo sapiens (Hsa) Hs9845293
(REC8L1)
GI:9845293
Homo sapiens (Hsa) Hs17461558 GI:17461558
Homo sapiens (Hsa) Hs18592523 GI:18592523
Saccharomyces cerevisiae (Sce) YDL003w
(S000002161)
GI:6320201 Q12158
Schizosaccharomyces pombe (Spo) SPBC29A10.14 GI:19112851 P36626
Schizosaccharomyces pombe (Spo) SPCC338.17c GI:19075651 P30776
Encephalitozoon cuniculi (Ecu) ECU04g1370 GI:19074216 Q8SVR5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IC
SpoSPBC29A10.14
GO:0000794 condensed nuclear chromosome C
IC
SpoSPCC338.17c
GO:0000798 nuclear cohesin complex C
ISS
AthAt5g40840
At3g59550
TAS
SceS000002161
GO:0000939 inner kinetochore of condensed
chromosome
C
IDA
SpoSPBC29A10.14
GO:0005634 nucleus C
IDA
CelCE02628
CE04726
SceS000002161
SpoSPCC338.17c
SPBC29A10.14
ISS
AthAt5g40840
At3g59550
GO:0005739 mitochondrion C
IDA
SpoSPCC338.17c
GO:0008278 cohesin complex C
IDA
SpoSPBC29A10.14
GO:0030892 mitotic cohesin complex C
IDA
SpoSPCC338.17c
GO:0030893 meiotic cohesin complex C
IDA
SpoSPBC29A10.14
GO:0003674 molecular_function F
ND
AthAt5g40840
At3g59550
SceS000002161
GO:0003684 damaged DNA binding F
ISS
CelCE02628
CE04726
GO:0005515 protein binding F
IPI
HsaO60216
SpoSPCC338.17c
SPBC29A10.14
GO:0000003 reproduction P
IMP
CelWBGene00004737
GO:0000724 double-strand break repair via homologous
recombination
P
IGI
SpoSPCC338.17c
GO:0006302 double-strand break repair P
IMP
SpoSPCC338.17c
TAS
HsaO60216
GO:0007059 chromosome segregation P
IMP
CelWBGene00000591
WBGene00004737
GO:0007064 mitotic sister chromatid cohesion P
IMP
SceS000002161
SpoSPCC338.17c
TAS
SceS000002161
GO:0007067 mitosis P
IEP
AthAt3g59550
At5g40840
GO:0007076 mitotic chromosome condensation P
IMP
SceS000002161
GO:0007126 meiosis P
IMP
CelWBGene00004737
WBGene00000591
GO:0007130 synaptonemal complex formation P
TAS
CelWBGene00000591
WBGene00004737
GO:0007131 meiotic recombination P
IMP
SpoSPBC29A10.14
TAS
HsaO60216
GO:0007626 locomotory behavior P
IMP
CelWBGene00000591
WBGene00004737
GO:0008608 attachment of spindle microtubules to
kinetochore
P
IMP
SpoSPCC338.17c
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004737
WBGene00000591
GO:0030999 linear element formation P
IMP
SpoSPBC29A10.14
GO:0040004 cuticular attachment to epithelium (sensu
Nematoda)
P
IMP
CelWBGene00004737
GO:0040007 growth P
IMP
CelWBGene00004737
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004737
GO:0042138 meiotic DNA double-strand break
formation
P
IMP
SpoSPBC29A10.14
GO:0045143 homologous chromosome segregation P
IDA
SpoSPBC29A10.14
GO:0045144 meiotic sister chromatid segregation P
IDA
SpoSPBC29A10.14
GO:0051177 meiotic sister chromatid cohesion P
IC
SpoSPBC29A10.14
GO:0051455 attachment of spindle microtubules to kinetochore
during meiosis I
P
IMP
SpoSPBC29A10.14
GO:0051754 meiotic sister chromatid cohesion,
centromeric
P
IGI
SpoSPBC29A10.14

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Inparanoid results:

Selected databases only

Inparanoid query cluster Phylogenetic pattern
S000002161

Species Link to cluster Score Model organism
protein page
UniProt link
Saccharomyces cerevisiae (Sce) query - S000002161
(YDL003W)
Canis familiaris (Cfa) 2033 1 ENSCAFP00000010177
Canis familiaris (Cfa) 2033 0.689 ENSCAFP00000001178
Takifugu rubripes (Fru) 2021 1 SINFRUP00000162508
Takifugu rubripes (Fru) 2021 0.537 SINFRUP00000136090
Gallus gallus (Gga) 1784 1 ENSGALP00000025921
(RCJMB04_5m6)
Gallus gallus (Gga) 1784 0.141 ENSGALP00000009968
(LOC419269)
Homo sapiens (Hsa) 2075 1 ENSP00000297338
(RAD21)
O60216
Homo sapiens (Hsa) 2075 0.147 ENSP00000246108
(RAD21L1)
Q9H4I0
Mus musculus (EMM) 2054 1 ENSMUSP00000022927
(MGI:108016)
Q3TG35
Mus musculus (EMM) 2054 1 ENSMUSP00000036780
Pan troglodytes (Ptr) 1912 1 ENSPTRP00000035102
Pan troglodytes (Ptr) 1912 0.15 ENSPTRP00000022521
Rattus norvegicus (ERN) 2010 1 ENSRNOP00000012752
(GI:682264)
Rattus norvegicus (ERN) 2010 0.683 ENSRNOP00000006209
(GI:314949)
Q4KLH7
Caenorhabditis elegans (Cel) 1710 1 WBGene00000591
(CE04726)
Caenorhabditis elegans (Cel) 1710 0.146 WBGene00004737
(CE02628)
Dictyostelium discoideum (Ddi) 1966 1 DDB0202625
Mus musculus (Mmu) 2015 1 MGI:108016 Q3TG35
Oryza sativa (Osa) 1493 1 Q7XYH6 Q7XYH6
Oryza sativa (Osa) 1493 0.995 Q6WG80 Q6WG80
Oryza sativa (Osa) 1493 0.135 Q8S0E7 Q8S0E7
Oryza sativa (Osa) 1493 0.128 Q9XFD8 Q9XFD8
Oryza sativa (Osa) 1493 0.074 Q6YTK0 Q6YTK0
Oryza sativa (Osa) 1493 0.069 Q6UFU8 Q6UFU8
Arabidopsis thaliana (Ath) 1739 1 NP_191514
(At3g59550.1)
Q9FQ19
Arabidopsis thaliana (Ath) 1739 0.099 NP_197131
(At5g16270.1)
Q8W1Y0
Arabidopsis thaliana (Ath) 1739 0.086 NP_851110
(At5g40840.1)
Arabidopsis thaliana (Ath) 1739 0.085 NP_568586
(At5g40840.2)
Q9FQ20


GO terms for Inparanoid results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000798 nuclear cohesin complex C
ISS
AthAt5g40840
At3g59550
TAS
SceS000002161
GO:0005622 intracellular C
RCA
MmuMGI:108016
GO:0005634 nucleus C
IDA
CelCE02628
CE04726
SceS000002161
ISS
AthAt5g40840
At3g59550
GO:0005840 ribosome C
RCA
MmuMGI:108016
GO:0003674 molecular_function F
ND
AthAt5g40840
At3g59550
SceS000002161
GO:0003684 damaged DNA binding F
ISS
CelCE02628
CE04726
GO:0003723 RNA binding F
RCA
MmuMGI:108016
GO:0003735 structural constituent of ribosome F
RCA
MmuMGI:108016
GO:0005515 protein binding F
IPI
HsaO60216
GO:0019843 rRNA binding F
RCA
MmuMGI:108016
GO:0000003 reproduction P
IMP
CelWBGene00004737
GO:0006302 double-strand break repair P
TAS
HsaO60216
GO:0006412 protein biosynthesis P
RCA
MmuMGI:108016
GO:0007059 chromosome segregation P
IMP
CelWBGene00000591
WBGene00004737
GO:0007064 mitotic sister chromatid cohesion P
IMP
SceS000002161
TAS
SceS000002161
GO:0007067 mitosis P
IEP
AthAt3g59550
At5g40840
GO:0007076 mitotic chromosome condensation P
IMP
SceS000002161
GO:0007126 meiosis P
IMP
CelWBGene00004737
WBGene00000591
GO:0007130 synaptonemal complex formation P
TAS
CelWBGene00000591
WBGene00004737
GO:0007131 meiotic recombination P
TAS
HsaO60216
GO:0007626 locomotory behavior P
IMP
CelWBGene00000591
WBGene00004737
GO:0009792 embryonic development (sensu Metazoa) P
IMP
CelWBGene00004737
WBGene00000591
GO:0040004 cuticular attachment to epithelium (sensu
Nematoda)
P
IMP
CelWBGene00004737
GO:0040007 growth P
IMP
CelWBGene00004737
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004737

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
80202

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) rad21
(SPCC338.17c)
GI:19075651 P30776
Saccharomyces cerevisiae (Sce) MCD1
(S000002161)
GI:6320201 Q12158
Kluyveromyces lactis (Kla) KLLA0F14795g GI:50311441 Q6CJZ4
Eremothecium gossypii (Ego) AEL007W GI:45190600
Magnaporthe grisea (Mgr) MG09891.4 GI:39964877
Neurospora crassa (Ncr) GeneID:2712439 GI:32420567